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描述 产品目录编号 14-681M 品牌系列 Upstate
商名 - Upstate
描述 Flt-4 Protein, active, 250 µg 概述 N-terminal GST-tagged, recombinant human Flt4, amino acids 800-end 应用 应用 Active, N-terminal GST-tagged, recombinant human Flt4, amino acids 800-end, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 expressed by baculovirus in Sf21 cells 品种 Human Entrez基因编号 - NM_182925.3
- NM_002020.3
基因符号 - VEGFR3
- FLT4
- PCL
- VEGFR-3
- FLT41
蛋白靶 Flt4 纯化方法 Glutathione-agarose 靶子系列 TK UniProt编号 - P35916
UniProt汇总 FUNCTION: SwissProt: P35916 # Receptor for VEGFC. Has a tyrosine-protein kinase activity.
SIZE: 1298 amino acids; 145599 Da
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
TISSUE SPECIFICITY: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain.
DISEASE: SwissProt: P35916 # Defects in FLT4 are the cause of hereditary lymphedema I [MIM:153100]; also known as Nonne-Milroy lymphedema or Milroy disease. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections and physical impairment. Hereditary lymphedema I shows autosomal dominant inheritance and is characterized by onset usually at birth. & Defects in FLT4 are found in juvenile hemangioma. Juvenile hemangiomas are the most common tumors of infancy, occurring as many as 10/% of all births. These benign vascular lesions enlarge rapidly during the first year of life by hyperplasia of endothelial cells and attendant pericytes, and then spontaneously involute over a period of years, leaving loose fibrofatty tissue.
SIMILARITY: SwissProt: P35916 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.产品使用声明 质量保证 routinely evaluated by phosphorylation of 500μM JAK3tide (Catalog # 12-547) 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C from date of shipment 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-681) and in bulk (cat# 14-681-K).
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下一件merck millipore产品：merck millipore,默克密理博,420323,InSolution™ KT5720 - CAS 108068-98-0 - Calbiochem
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