merck millipore,默克密理愽
  • merck millipore,默克密理博,9081,Human Leptin

  • merck millipore,默克密理博,9081,Human Leptin

    产品名称：Human Leptin
    产品型号：9081
    Iodinated Human Leptin -HPLC purified & prepared fresh monthly.

    merck millipore,默克密理博,9081,Human Leptin

  • 产品介绍
  • merck millipore,默克密理博,9081,Human Leptin

    描述
    产品目录编号 9081
    描述 Human Leptin
    背景信息 These iodinated hormonos are HPLC purified and prepared fresh monthly.
    应用
    应用 Iodinated Human Leptin -HPLC purified & prepared fresh monthly.
    应用说明 appropriate label hydrating buffer if kit replacement or assay buffer of choice
    生物信息
    品种 Human
    Entrez基因编号
    • NM_000230.1
    Entrez基因汇总 This gene encodes a protein that is secreted by white adipocytes, and which plays a major role in the regulation of body weight. This protein, which acts through the leptin receptor, functions as part of a signaling pathway that can inhibit food intake and/or regulate energy expenditure to maintain constancy of the adipose mass. This protein also has several endocrine functions, and is involved in the regulation of immune and inflammatory responses, hematopoiesis, angiogenesis and wound healing. Mutations in this gene and/or its regulatory regions cause severe obesity, and morbid obesity with hypogonadism. This gene has also been linked to type 2 diabetes mellitus development.
    基因符号
    • OBS
    • LEP
    • leptin
    • OB
    • obesity
    标签 125Iodine
    UniProt编号
    • P41159
    UniProt汇总 FUNCTION: SwissProt: P41159 # May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass.
    SIZE: 167 amino acids; 18641 Da
    SUBUNIT: Interacts with SIGLEC6.
    SUBCELLULAR LOCATION: Secreted.
    DISEASE:SwissProt: P41159 # Defects in LEP may be a cause of autosomal recessive obesity [MIM:601665].
    SIMILARITY: SwissProt: P41159 ## Belongs to the leptin family.
    理化信息
    放射性 <3 μCi
    储存和货运信息
    存储条件 2–8 °C
    包装信息
    数量 250 tubes

    merck millipore,默克密理博,9081,Human Leptin

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