merck millipore,默克密理愽
  • merck millipore,默克密理博,488230,Nogo-66 (1-40) Antagonist Peptide, Synthetic - Calbiochem

  • merck millipore,默克密理博,488230,Nogo-66 (1-40) Antagonist Peptide, Synthetic - Calbiochem

    产品名称：Nogo-66 (1-40) Antagonist Peptide, Synthetic - Calbiochem
    产品型号：488230
    The Nogo-66 (1-40) Antagonist Peptide, Synthetic controls the biological activity of Nogo-66 (1-40). This small molecule/inhibitor is primarily used for Neuroscience applications.

    merck millipore,默克密理博,488230,Nogo-66 (1-40) Antagonist Peptide, Synthetic - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,488230,Nogo-66 (1-40) Antagonist Peptide, Synthetic - Calbiochem

    重要规格表

    经验配方
    C₂₀₆H₃₂₄N₅₆O₆₅
    描述
    概述 An end-protected 40-mer peptide derived from the N-terminal fragment of the Nogo-66 domain that acts as a selective, competitive, high affinity antagonist of Nogo-66 receptor (NgR). Although NgR serves as the common receptor for both Nogo-66 and MAG (myelin-associated glycoprotein), NEP1-40 blocks only the inhibition of neurite outgrowth induced by Nogo-66, but not that by MAG. Promotes axonal regeneration after spinal cord injury in rats.
    产品目录编号 488230
    品牌系列 Calbiochem®
    同义词 Nogo Extracellular Peptide, 1-40, NEP1-40, Ac-RIYKGVIQAIQKSDEGHPFRAYLESEVAISEELVQKYSNS-NH₂
    参考
    参考 GrandPré, T., et al. 2002. Nature 417, 547.
    Liu, B.P., et al. 2002. Science 297, 1190.
    产品信息
    具有ATP竞争性 Y
    形式 White solid
    配方 Supplied as a trifluoroacetate salt.
    Hill配方 C₂₀₆H₃₂₄N₅₆O₆₅
    化学配方 C₂₀₆H₃₂₄N₅₆O₆₅
    Molar Mass 4625.2
    吸湿 Hygroscopic
    肽序列 Ac-Arg-Ile-Tyr-Lys-Gly-Val-Ile-Gln-Ala-Ile-Gln-Lys-Ser-Asp-Glu-Gly-His-Pro-Phe-Arg-Ala-Tyr-Leu-Glu-Ser-Glu-Val-Ala-Ile-Ser-Glu-Glu-Leu-Val-Gln-Lys-Tyr-Ser-Asn-Ser-NH₂
    可逆 N
    生物信息
    主靶 Nogo-66 receptor (NgR)
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 N
    溶解度 DMSO
    肽序列 Ac-Arg-Ile-Tyr-Lys-Gly-Val-Ile-Gln-Ala-Ile-Gln-Lys-Ser-Asp-Glu-Gly-His-Pro-Phe-Arg-Ala-Tyr-Leu-Glu-Ser-Glu-Val-Ala-Ile-Ser-Glu-Glu-Leu-Val-Gln-Lys-Tyr-Ser-Asn-Ser-NH₂
    储存和货运信息
    货运代码 Blue Ice Only
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    吸湿 Hygroscopic
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,488230,Nogo-66 (1-40) Antagonist Peptide, Synthetic - Calbiochem

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