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merck millipore,默克密理博,616400,Tranilast - CAS 53902-12-8 - Calbiochem
产品名称:Tranilast - CAS 53902-12-8 - Calbiochem
产品型号:616400
An anthranilic acid analog that acts as a potent inhibitor of VEGF- and vascular permeability factor-induced angiogenesis and collagen synthesis.
merck millipore,默克密理博,616400,Tranilast - CAS 53902-12-8 - Calbiochem
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重要规格表
经验配方 CAS号 C₁₈H₁₇NO₅ 53902-12-8 描述 概述 An anthranilic acid analog that acts as a potent inhibitor of VEGF- and vascular permeability factor-induced angiogenesis and collagen synthesis. Inhibits VEGF- and PMA-stimulated PKC activity in retinal capillary endothelial cells without affecting the VEGF binding or VEGF receptor phosphorylation. Also has antiallergic, anti-inflammatory, and antiproliferative properties. Induces Ca2+ mobilization in vascular smooth muscle. 产品目录编号 616400 品牌系列 Calbiochem®
同义词 N-(3ʹ,4ʹ-Dimethoxycinnamoyl)anthranilic Acid 参考 参考 Koyama, S., et al. 1999. Br. J. Pharmacol. 127, 537.
Isaji, M., et al. 1998. Life Sci. 63, PL71.
Isaji, M., et al. 1997. Br. J. Pharmacol. 122, 1061.产品信息 CAS号 53902-12-8 具有ATP竞争性 N 形式 Pale yellow solid Hill配方 C₁₈H₁₇NO₅ 化学配方 C₁₈H₁₇NO₅ Molar Mass 327.3 可逆 N 结构配方图像 生物信息 主靶 VEGF- and vascular permeability factor-induced angiogenesis and collagen synthesis 纯度 ≥95% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO GHS安全信息 RTECS DG8731000 安全信息 R相 R: 20/21/22
Harmful by inhalation, in contact with skin and if swallowed.S相 S: 36
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Harmful
储存 -20°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). 包装信息 惰性气体下包装 Packaged under inert gas
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