merck millipore,默克密理愽
  • merck millipore,默克密理博,AB1889,Anti-C-C Chemokine Receptor 5 Antibody, NT

  • merck millipore,默克密理博,AB1889,Anti-C-C Chemokine Receptor 5 Antibody, NT

    产品名称：Anti-C-C Chemokine Receptor 5 Antibody, NT
    产品型号：AB1889
    Anti-C-C Chemokine Receptor 5 Antibody, N-terminus is an antibody against C-C Chemokine Receptor 5 for use in WB.

    merck millipore,默克密理博,AB1889,Anti-C-C Chemokine Receptor 5 Antibody, NT

  • 产品介绍
  • merck millipore,默克密理博,AB1889,Anti-C-C Chemokine Receptor 5 Antibody, NT

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HWBRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 AB1889
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-C-C Chemokine Receptor 5 Antibody, NT
    Alternate Names
    • CD195
    • CCR-5
    背景信息 HIV and related viruses require coreceptors, in addition to CD4, to infect target cells. Some G-protein-coupled receptors including CCR5, CXCR4, CCR3, CCR2b and CCR8 in the chemokine receptor family, and four new human molecules GPR15, STRL33, GPR1 and V28 were recently identified as HIV coreceptors (1,2). Among them, CCR5 is a principle coreceptor for macrophage- and dual-tropic HIV-1 strains fusion of entry of human white blood cells (3,4). The amino-terminal domain and the extracellular loops of CCR5 serve as HIV binding sites. CCR5 messenger RNA is expressed in lymphoid organs and monocytes.
    产品信息
    格式 Purified
    演示 Purified immunoglobulin. 100 μg purified IgG in 100 μL of PBS containing 0.2% sodium azide.
    应用
    应用 Anti-C-C Chemokine Receptor 5 Antibody, N-terminus is an antibody against C-C Chemokine Receptor 5 for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western blot: 1:1000 - 1:2000 (THP-1 whole cell lysate can be used as a positive control)

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Synthetic peptide from the N-terminal domain of human CCR5.
    表位 N-terminus
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Specific for human C-C Chemokine Receptor 5 (CCR5) at the N-terminus.
    品种反应性 Human
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_001100168.1
    • NM_000579.3
    Entrez基因汇总 This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta) and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor gene cluster region. Two transcript variants encoding the same protein have been found for this gene.
    基因符号
    • CCR-5
    • CCR5
    • CCCKR5
    • CMKBR5
    • chemr13
    • CD195
    • CKR5
    • CHEMR13
    • CC-CKR-5
    • CKR-5
    UniProt编号
    • P51681
    UniProt汇总 FUNCTION: SwissProt: P51681 # Receptor for a C-C type chemokine. Binds to MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ions level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
    SIZE: 352 amino acids; 40524 Da
    SUBUNIT: Interacts with PRAF2. Interacts with HIV-1 surface protein gp120.
    SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Found in promyelocytic cells.
    PTM: Sulfation contributes to the efficiency of HIV-1 entry. & O-glycosylated, but not N-glycosylated.
    SIMILARITY: SwissProt: P51681 ## Belongs to the G-protein coupled receptor 1 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2-8°C for up to 12 months.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,AB1889,Anti-C-C Chemokine Receptor 5 Antibody, NT

上一件merck millipore产品：merck millipore,默克密理博,ST1661,Anti-MSLN Rabbit pAb
下一件merck millipore产品：merck millipore,默克密理博,23-026,SCF-TrCP1 Protein Complex, Active, 10 µg


相关产品

merck millipore,默克密理博,539624,PKCζ Pseudosubstrate Inhibitor, Myristoylated - Calbiochem merck millipore,默克密理博,539624,PKCζ Pseudosubstrate Inhibitor, Myristoylated - Calbiochem

merck millipore,默克密理博,MAB10225,Anti-Lipoprotein H2 Antibody, clone MA1-6,MAB10225 merck millipore,默克密理博,MAB10225,Anti-Lipoprotein H2 Antibody, clone MA1-6,MAB10225

merck millipore,默克密理博,119123,Adenosine 5ʹ-O-(3-Thiotriphosphate), Solution, Tetralithium Salt - CAS 93839-89-5 - Calbiochem merck millipore,默克密理博,119123,Adenosine 5ʹ-O-(3-Thiotriphosphate), Solution, Tetralithium Salt - CAS 938...

merck millipore,默克密理博,251505,DAF-2 DA - CAS 205391-02-2 - Calbiochem merck millipore,默克密理博,251505,DAF-2 DA - CAS 205391-02-2 - Calbiochem

merck millipore,默克密理博,ST1661,Anti-MSLN Rabbit pAb merck millipore,默克密理博,ST1661,Anti-MSLN Rabbit pAb

merck millipore,默克密理博,23-026,SCF-TrCP1 Protein Complex, Active, 10 µg merck millipore,默克密理博,23-026,SCF-TrCP1 Protein Complex, Active, 10 µg

merck millipore,默克密理博,ABE611,Anti-RRM1 Antibody merck millipore,默克密理博,ABE611,Anti-RRM1 Antibody

merck millipore,默克密理博,AB2202,Anti-PER2 Antibody merck millipore,默克密理博,AB2202,Anti-PER2 Antibody

merck millipore,默克密理博,219012,Caspase-3 Inhibitor VII - CAS 745046-84-8 - Calbiochem merck millipore,默克密理博,219012,Caspase-3 Inhibitor VII - CAS 745046-84-8 - Calbiochem

merck millipore,默克密理博,616400,Tranilast - CAS 53902-12-8 - Calbiochem merck millipore,默克密理博,616400,Tranilast - CAS 53902-12-8 - Calbiochem


whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部