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品种反应性 主要应用 宿主 抗体类型 R, M WB Rb Polyclonal Antibody 描述 产品目录编号 AB2202 商名 - Chemicon
描述 Anti-PER2 Antibody 背景信息 PER2 is a component of the circadian clock mechanism which is essential for generating circadian rhythms. It is a negative element in the circadian transcriptional loop by Influencing clock function by interacting with other circadian regulatory proteins and transporting them to the nucleus. PER2 negatively regulates CLOCK NPAS2-BMAL1 BMAL2-induced transactivation. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known. 产品信息 控制 - C2C12 tissue lysate.
演示 Serum with 0.05% NaN3 应用 应用 Anti-PER2 Antibody detects level of PER2 & has been published & validated for use in WB. 主要应用 - Western Blotting
应用说明 Western Blot Analysis:
C2C12 lysate was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-PER2 (1:500 dilution of this lot). Proteins were visualized using a Donkey anti-rabbit secondary antibody conjugated to HRP and a chemiluminescence detection system.生物信息 免疫原品种 Synthetic peptide. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Cat. # AB2202 will recognize the N-terminus of PER2. 品种反应性 RatMouse Species Reactivity Note Mouse and Rat. Reactivity with other species has not been determined. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_035196
基因符号 - hPER2
- FASPS
- KIAA0347
UniProt编号 - O54943
产品使用声明 质量保证 Routinely evaluated by western blot on C2C12 lysate. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 1 year after date of receipt. 包装信息 数量 100 µL
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