merck millipore,默克密理愽
  • merck millipore,默克密理博,573121,SMER28 - CAS 307538-42-7 - Calbiochem

  • merck millipore,默克密理博,573121,SMER28 - CAS 307538-42-7 - Calbiochem

    产品名称：SMER28 - CAS 307538-42-7 - Calbiochem
    产品型号：573121
    A cell-permeable quinazoline compound that augments the cytostatic effects of Rapamycin and acts as an autophagy stimulator both in mammalian cultures in vitro and in a Drosophila melanogast More>>

    merck millipore,默克密理博,573121,SMER28 - CAS 307538-42-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,573121,SMER28 - CAS 307538-42-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₁H₁₀BrN₃307538-42-7
    描述
    概述 A cell-permeable quinazoline compound that augments the cytostatic effects of Rapamycin (Cat. Nos. 553210 and 553211) in Saccharomyces cerevisiae and acts as an autophagy stimulator both in mammalian cultures in vitro and in a Drosophila melanogaster HD model in vivo. Although SMER28 and Rapamycin do exhibit additive effects on the clearance of cellular autophagy substrates, SMER28 functions independently of Rapamycin by presumably acting on celluar target(s) downstream of the Rapamycin/FKBP12 target, mTOR.
    产品目录编号 573121
    品牌系列 Calbiochem®
    同义词 (6-Bromo-4-allylamino)quinazoline, Small-Molecule Enhancer of Rapamycin-28, Autophagy Inducer II
    参考
    参考 Tian, Y., et al. 2011. FASEB J. 25, 1934. Sarkar, S., et al. 2007. Nat. Chem. Biol. 3, 331.
    产品信息
    CAS号 307538-42-7
    形式 Pale yellow solid
    Hill配方 C₁₁H₁₀BrN₃
    化学配方 C₁₁H₁₀BrN₃
    Molar Mass 264.1
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,573121,SMER28 - CAS 307538-42-7 - Calbiochem

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