merck millipore,默克密理博,ABS701,Anti-RCC1 Antibody

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merck millipore,默克密理博,ABS701,Anti-RCC1 Antibody
产品名称：Anti-RCC1 Antibody
产品型号：ABS701
Detect RCC (regulator of chromatin condensation) using this rabbit polyclonal antibody, Anti-RCC1 Antibody validated for use in western blotting.

merck millipore,默克密理博,ABS701,Anti-RCC1 Antibody

产品介绍

merck millipore,默克密理博,ABS701,Anti-RCC1 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	WB	Rb	Purified	Polyclonal Antibody

描述
产品目录编号	ABS701
描述	Anti-RCC1 Antibody
Alternate Names	CHC1 Regulator of chromosome condensation RCC1 Cell cycle regulatory protein Chromosome condensation protein 1
背景信息	The Regulator of Chromosome Condensation 1 (RCC1) is a guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. RCC1 is a critical cell cycle regulator, and it interacts with Ran, a nuclear GTP-binding protein. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Studies have shown that RCC1 plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly. RCC1 is involved in regulating the onset of chromosome condensation during S phase. The RCC1 protein binds both to the nucleosomes and double-stranded DNA. The RCC1 complex acts as a guanine-nucleotide dissociation stimulator (GDS) by promoting the loss of bound GDP and the uptake of fresh GTP. Mutations in RCC1 have been assiciated with Raynaud disease.

产品信息
格式	Purified
演示	Purified rabbit polyclonal antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide and 50% glycerol.

应用
应用	Detect RCC (regulator of chromatin condensation) using this rabbit polyclonal antibody, Anti-RCC1 Antibody validated for use in western blotting.
主要应用	Western Blotting

生物信息
免疫原品种	Partial recombinant protein corresponding to the N-terminus of human RCC1.
宿主	Rabbit
同种型	IgG
品种反应性	Human
抗体类型	Polyclonal Antibody
基因符号	CHC1 RCC1
纯化方法	Antigen Affinity purified
UniProt编号	P18754

产品使用声明
质量保证	Western Blotting Analysis: 10 μL of this antibody detected RCC1 in HeLa nuclear extract.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.