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merck millipore,默克密理博,553512,InSolution™ Rac1 Inhibitor II, Z62954982 - CAS 1090893-12-1 - Calbiochem
产品名称：InSolution™ Rac1 Inhibitor II, Z62954982 - CAS 1090893-12-1 - Calbiochem
产品型号：553512
The InSolution™ Rac1 Inhibitor II, Z62954982, also referenced under CAS 1090893-12-1, controls the biological activity of Rac1. This small molecule/inhibitor is primarily used for Phosphorylation & De More>>
merck millipore,默克密理博,553512,InSolution™ Rac1 Inhibitor II, Z62954982 - CAS 1090893-12-1 - Calbiochem
- 产品介绍
- merck millipore,默克密理博,553512,InSolution™ Rac1 Inhibitor II, Z62954982 - CAS 1090893-12-1 - Calbiochem
重要规格表
经验配方 CAS号 C₂₀H₂₁N₃O₅S 1090893-12-1 描述 概述 A cell-permeable isoxazolyl-benzamide compound that is more effective than NSC23766 (Cat. Nos. 553502 & 553508) in inhibiting PDGF-BB- (Cat. No. 521225) induced cellular Rac1 activation (45.8% vs 11.1% inhibition by 4 h pretreatment of the respective compound at 50 µM) in serum-starved SMCs (human aortic smooth muscle cells) by interfering Rac1-Tiam1 interaction, while exhibiting no effect toward cellular Cdc42 and RhoA activation or Rac1 interaction to its effector Pak1. Shown to effectively prevent PDGF-BB-induced membrane ruffling and lamellipodia formation in serum-starved 3T3 cells (4 h pretreatment at 25 µM). The solid form of this compound (Cat. No. 553511) is also available. 产品目录编号 553512 品牌系列 Calbiochem®
同义词 Z62954982, 3-((3,5-Dimethylisoxazol-4-yl)methoxy)-N-(4-methyl-3-sulfamoyl-phenyl)benzamide 参考 参考 Ferri, N., et al. 2009. J. Med. Chem. 52, 4087. 产品信息 CAS号 1090893-12-1 形式 Liquid 配方 A 100 mM (10 mg/241 µl) solution of Rac1 Inhibitor II, Z62954982 (Cat. No. 553511) in DMSO Hill配方 C₂₀H₂₁N₃O₅S 化学配方 C₂₀H₂₁N₃O₅S Molar Mass 415.5 吸湿 Hygroscopic
结构配方图像 生物信息 纯度 ≥93% by HPLC 安全信息 R相 R: 36/38
Irritating to eyes and skin.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Blue Ice Only
毒性 Irritant
储存 -20°C
避光 Protect from light
吸湿 Hygroscopic
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-20°C). 包装信息 惰性气体下包装 Packaged under inert gas
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