• merck millipore,默克密理博,14-681,Flt-4 Protein, active, 10 µg
  • merck millipore,默克密理博,14-681,Flt-4 Protein, active, 10 µg

    产品名称:Flt-4 Protein, active, 10 µg
    产品型号:14-681
    Active, N-terminal GST-tagged, recombinant human Flt4, amino acids 800-end, for use in Kinase Assays.

    merck millipore,默克密理博,14-681,Flt-4 Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-681,Flt-4 Protein, active, 10 µg

    描述
    产品目录编号 14-681
    品牌系列 Upstate
    商名
    • Upstate
    描述 Flt-4 Protein, active, 10 µg
    概述 N-terminal GST-tagged, recombinant human Flt4, amino acids 800-end
    应用
    应用 Active, N-terminal GST-tagged, recombinant human Flt4, amino acids 800-end, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed by baculovirus in Sf21 cells
    品种 Human
    Entrez基因编号
    • NM_182925.3
    • NM_002020.3
    基因符号
    • VEGFR3
    • FLT4
    • PCL
    • VEGFR-3
    • FLT41
    蛋白靶 Flt4
    纯化方法 Glutathione-agarose
    靶子系列 TK
    UniProt编号
    • P35916
    UniProt汇总 FUNCTION: SwissProt: P35916 # Receptor for VEGFC. Has a tyrosine-protein kinase activity.
    SIZE: 1298 amino acids; 145599 Da
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    TISSUE SPECIFICITY: Placenta, lung, heart, and kidney, does not seem to be expressed in pancreas and brain.
    DISEASE: SwissProt: P35916 # Defects in FLT4 are the cause of hereditary lymphedema I [MIM:153100]; also known as Nonne-Milroy lymphedema or Milroy disease. Hereditary lymphedema is a chronic disabling condition which results in swelling of the extremities due to altered lymphatic flow. Patients with lymphedema suffer from recurrent local infections and physical impairment. Hereditary lymphedema I shows autosomal dominant inheritance and is characterized by onset usually at birth. & Defects in FLT4 are found in juvenile hemangioma. Juvenile hemangiomas are the most common tumors of infancy, occurring as many as 10/% of all births. These benign vascular lesions enlarge rapidly during the first year of life by hyperplasia of endothelial cells and attendant pericytes, and then spontaneously involute over a period of years, leaving loose fibrofatty tissue.
    SIMILARITY: SwissProt: P35916 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. & Contains 7 Ig-like C2-type (immunoglobulin-like) domains. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of 500μM JAK3tide (Catalog # 12-547)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C from date of shipment
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-681,Flt-4 Protein, active, 10 µg

上一件merck millipore产品:merck millipore,默克密理博,ABC35,Anti-HRS (HGS) Antibody
下一件merck millipore产品:merck millipore,默克密理博,ABE152,Anti-phospho-Histone H3 (Ser31) Antibody



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