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纯度 ≥97% by SDS-PAGE 描述 概述 Recombinant, mouse betacellulin (BTC) cinsisting of amino acids 32-118 and expressed in E. coli. Mouse BTC is 93% identical to the amino acid sequence of rat and 79% with that of human. BTC, a heparin-binding protein, is expressed in tissues such as uterus, liver, pancreas, and kidney and promotes pancreatic beta-cell growth and differentiation. Also known as a potent mitogen for retinal pigment epithelial cells, fibroblasts, and vascular smooth muscle cells. 产品目录编号 200497 品牌系列 Calbiochem®
参考 参考 Bastian, S.E., et al. 2001. J. Endocrinol. 168, 203.
Li, L., et al. 2001. Endocrinology 142, 5379.
Dunbar, A.J. and C. Goddard. 2000. Int. J. Biochem. Cell Biol. 32, B805.
Tada, H., et al. 1999. J. Cell Biochem. 72, 423.
Pathak, B.G., et al. 1995. Genomics 28, 116.
Shing, Y., et al. 1993. Science 259, 1604.产品信息 形式 Liquid 配方 Lyophilized from 0.2 µm sterile-filtered PBS, BSA. 生物信息 生物活性 ED₅₀ = 0.15-0.6 ng/ml as measured in a cell proliferation assay using Balb/3T3 mouse embryonic fibroblasts. 纯度 ≥97% by SDS-PAGE 理化信息 污染物 Endotoxin: <1.0 Eu/µg protein 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.
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