• merck millipore,默克密理博,529579,PP1 Analog - CAS 221243-82-9 - Calbiochem
  • merck millipore,默克密理博,529579,PP1 Analog - CAS 221243-82-9 - Calbiochem

    产品名称:PP1 Analog - CAS 221243-82-9 - Calbiochem
    产品型号:529579


    merck millipore,默克密理博,529579,PP1 Analog - CAS 221243-82-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,529579,PP1 Analog - CAS 221243-82-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₉H₁₉N₅221243-82-9
    描述
    概述 A potent, reversible, ATP-competitive, and cell-permeable inhibitor of Src-family tyrosine kinases that is > 800 times more selective for the I338G mutant v-Src (IC50 = 1.5 nM) compared to wild-type v-Src (IC50 = 1.0 µM). Also inhibits wild-type Fyn (IC50 = 600 nM). Also available in InSolution™ format (Cat. No. 529605).
    产品目录编号 529579
    品牌系列 Calbiochem®
    同义词 4-Amino-1-tert-butyl-3-(1ʹ-naphthyl)pyrazolo[3,4-d]pyrimidine, 1-Na PP1, 1-NA-PP1
    参考
    参考 Bishop, A.C., et al. 2000. Nature 407, 395.
    Bishop, A.C., et al. 1999 J. Am. Chem. Soc. 121, 627.
    产品信息
    CAS号 221243-82-9
    具有ATP竞争性 Y
    声明

    Not available for sale in the United States.

    形式 Off-white solid
    Hill配方 C₁₉H₁₉N₅
    化学配方 C₁₉H₁₉N₅
    Molar Mass 317.4
    可逆 Y
    结构配方图像
    生物信息
    主靶 I338G mutant v-Src
    主靶IC50 1.5 nM against I338G mutant v-Src; 1.0 µM against wild-type v-Src; 600 nM against wild-type Fyn
    纯度 ≥99% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, refrigerate (4°C). Stock solutions are stable for up to 3 months at 4°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,529579,PP1 Analog - CAS 221243-82-9 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,05-786,Anti-phospho-SMC1 (Ser957) Antibody, clone 5D11G5
下一件merck millipore产品:merck millipore,默克密理博,12-532,SRPKtide



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