merck millipore,默克密理愽
  • merck millipore,默克密理博,370653,PknG Inhibitor - CAS 329221-38-7 - Calbiochem

  • merck millipore,默克密理博,370653,PknG Inhibitor - CAS 329221-38-7 - Calbiochem

    产品名称：PknG Inhibitor - CAS 329221-38-7 - Calbiochem
    产品型号：370653
    The PknG Inhibitor, also referenced under CAS 329221-38-7, controls the biological activity of PknG. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation application More>>

    merck millipore,默克密理博,370653,PknG Inhibitor - CAS 329221-38-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,370653,PknG Inhibitor - CAS 329221-38-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₃H₁₆N₂O₂S329221-38-7
    描述
    概述 A cell-permeable tetrahydrobenzothiophene compound that acts as a highly specific and ATP-binding site-targeting inhibitor against mycobacterial protein kinase G (PknG; IC50 = 390 nM), while exhibiting much reduced or no activity against 8 other mycobacterial and 25 other human kinases, including PKCα, the mammalian kinase most closely related to PknG. AX20017 is shown to completely inactivate PknG-mediated blockage of lysosomal transfer and degradation of M. bovis BCG in macrophages at concentrations (10µM or higher) that does not otherwise affect the growth of BCG outside its infected host.
    产品目录编号 370653
    品牌系列 Calbiochem®
    同义词 Mycobacterial Protein Kinase G Inhibitor, 2-(Cyclopropanecarbonylamino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide, AX20017
    参考
    参考 Scherr, N., et al. 2007. Proc. Natl. Acad. Sci. USA 104, 16388.
    Walburger, A., et al. 2004. Science 304, 1800.
    产品信息
    CAS号 329221-38-7
    形式 Light brown solid
    Hill配方 C₁₃H₁₆N₂O₂S
    化学配方 C₁₃H₁₆N₂O₂S
    Molar Mass 264.3
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,370653,PknG Inhibitor - CAS 329221-38-7 - Calbiochem

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