merck millipore,默克密理愽
  • merck millipore,默克密理博,479975,NDGA - CAS 500-38-9 - Calbiochem

  • merck millipore,默克密理博,479975,NDGA - CAS 500-38-9 - Calbiochem

    产品名称：NDGA - CAS 500-38-9 - Calbiochem
    产品型号：479975
    A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC₅₀ = 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC₅₀ = 100 µM).

    merck millipore,默克密理博,479975,NDGA - CAS 500-38-9 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,479975,NDGA - CAS 500-38-9 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₈H₂₂O₄500-38-9
    描述
    概述 A cell-permeable antioxidant and a selective lipoxygenase (LOX) inhibitor (IC50 = 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively) over cyclooxygenase (IC50 = 100 µM). Also shown to inhibit platelet-derived growth factor (PDGF)-stimulated DNA synthesis in Swiss/3T3 cells. A powerful hydroxy radical quencher.
    产品目录编号 479975
    品牌系列 Calbiochem®
    同义词 Nordihydroguaiaretic Acid
    参考
    参考 Domin, J., et al. 1994. J. Biol. Chem. 269, 8260.
    Goodman, Y., et al. 1994. Brain Res. 654, 171.
    Kozubik, A., et al. 1993. Exp. Hematol. 21, 138.
    Salari, H., et al. 1984. Prostagland. Leuk. Med. 13, 53.
    Hope, W.C., et al. 1983. Biochem. Pharmacol. 32, 367.
    产品信息
    CAS号 500-38-9
    具有ATP竞争性 N
    形式 Crystalline solid
    Hill配方 C₁₈H₂₂O₄
    化学配方 C₁₈H₂₂O₄
    Molar Mass 302.4
    可逆 N
    结构配方图像
    生物信息
    主靶 LOX-5
    主靶IC50 200 nM, 30 µM, and 30 µM for 5-LOX, 12-LOX, and 15-LOX, respectively
    纯度 ≥90% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    GHS安全信息
    RTECS UX1750000
    安全信息
    R相 R: 22-36/37/38

    Harmful if swallowed.
    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 +15°C to +30°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,479975,NDGA - CAS 500-38-9 - Calbiochem

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