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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT303 描述 Anti-PITRM1 Antibody Alternate Names - PITRM1
- Presequence protease, mitochondrial
- hPreP
- Pitrilysin metalloproteinase 1
- Metalloprotease 1
- hMP1
背景信息 PITRM1 (Presequence protease, mitochondrial) is an ATP-independent protease that degrades mitochondrial transit peptides after their cleavage. It is specific for peptides in the range of 10 to 65 residues and able to degrade amyloid beta A4 (APP) protein when it accumulates in mitochondrion, suggesting a link with Alzheimer's disease. PITRM1 shows a preference for cleavage after small polar residues and before basic residues, but without any positional reference. 产品信息 格式 Affinity Purified 控制 - Human placenta tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.1% sodium azide and 50% glycerol. 应用 应用 This PITRM1 antibody is validated for use in WB for the detection of the PITRM1 protein. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human PITRM1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHuman Species Reactivity Note Demonstrated to react with Human and Mouse. 抗体类型 Polyclonal Antibody 基因符号 - MP1
- PITRM1
纯化方法 Antigen Affinity purified UniProt编号 - Q5JRX3
产品使用声明 质量保证 Evaluated by Western Blotting in human placenta tissue lysate.
Western Blotting Analysis: A 1:300 dilution of this antibody detected PITRM1 in 30 µg of human placenta tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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