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merck millipore,默克密理博,04-123,Anti-TAL-1 Antibody, clone BTL73
产品名称：Anti-TAL-1 Antibody, clone BTL73
产品型号：04-123
Use Anti-TAL-1 Antibody, clone BTL73 (Mouse Monoclonal Antibody) validated in WB, IHC to detect TAL-1 also known as SCL, T-cell acute lymphocytic leukemia 1, TCL5, TAL-1, Stem cell protein.
merck millipore,默克密理博,04-123,Anti-TAL-1 Antibody, clone BTL73
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB M Affinity Purified Monoclonal Antibody 描述 产品目录编号 04-123 品牌系列 Upstate
商名 - Upstate
描述 Anti-TAL-1 Antibody, clone BTL73 Alternate Names - Stem cell protein
- SCL
- T-cell acute lymphocytic leukemia 1
- TCL5
- TAL-1
背景信息 TAL-1, also known as SCL (stem cell leukemia), is a serine phosphoprotein and basic-helix-loop-helix transcription factor. TAL-1 is implicated in the genesis of hemopoietic malignancies and is a positive regulator of erythroid differentiation. A nonrandom, site-specific TAL-1 chromosomal translocation is commonly associated with oncogenic transformation in many T-cell acute lymphoblastic leukemias. TAL-1 binds to the LIM domain containing protein Rhombotin 2 (RBTN2), where it forms a complex with GATA1 or GATA 2 that is essential for erythropoiesis. 产品信息 格式 Affinity Purified 控制 - Jurkat cell lysate
演示 Purified mouse monoclonal IgG1k in buffer containing PBS and 0.05% sodium azide. 应用 应用 Use Anti-TAL-1 Antibody, clone BTL73 (Mouse Monoclonal Antibody) validated in WB, IHC to detect TAL-1 also known as SCL, T-cell acute lymphocytic leukemia 1, TCL5, TAL-1, Stem cell protein. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blot Analysis: 2 μg/mL of this lot detected a strong 44 kDa of PP42-TAL1 in Jurkat cell lysate, and also very faint PP24-TAL. Optimal working dilutions must be determined by the end user. 生物信息 免疫原品种 Recombinant GST-TAL1 (K Pulford, et al., 1995, Blood, 85: 675 - 684) 表位 C-Terminus 克隆 clone BTL73 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody detects two predominant protein products of the SCL/TAL1 gene in T cell acute lymphoblastic leukemia (T-ALL): a full length PP42-TAL1 (42/44 kDa) and a truncated form PP24-TAL1 (24/26 kDa). 同种型 IgG1κ 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_003180
基因符号 - TCL5
- TAL1
- SCL
纯化方法 Protein G purfied UniProt编号 - P17542
产品使用声明 质量保证 Routinely evaluated by western blot on Jurkat cell lysate. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. 包装信息 数量 100 µg
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