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merck millipore,默克密理博,ABF278,Anti-IL-17F (human), Alexa Fluor 488, clone Poly5166 Antibody
产品名称:Anti-IL-17F (human), Alexa Fluor 488, clone Poly5166 Antibody
产品型号:ABF278
Anti-IL-17F (human), Alexa Fluor 488, clone Poly5166 Antibody is a highly specific goat polyclonal antibody & that targets IL-17 & has been tested in Flow Cytometry.
merck millipore,默克密理博,ABF278,Anti-IL-17F (human), Alexa Fluor 488, clone Poly5166 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H FC Gt AlexaFluor®488 Polyclonal Antibody 描述 产品目录编号 ABF278 描述 Anti-IL-17F (human), Alexa Fluor® 488, clone Poly5166 Antibody Alternate Names - IL-24
- Interleukin-17F
- IL-17F
- Cytokine ML-1
- Interleukin-24
背景信息 IL-17F is a member of the IL-17 cytokine family which consists of at least seven structurally related proteins (IL-17A, B, C, D, E, F, and A/F). IL-17F homodimer adopts a cystine knot motif formed through the interactions of four cysteines, one of which is responsible for inter-chain bonding. IL-17F is most closely related to IL-17A, sharing 50% amino acid sequence homology. IL-17F is expressed in activated Th17 cells, along with IL-17A homodimers and IL-17A/F heterodimers. It is also expressed in activated, but not resting, CD4+ T-cells, and activated monocytes. IL-17F has been shown to inhibit endothelial cell angiogenesis and induce increased production of IL-2, TGF-b, and MCP-1, playing a critical role in the regulation of inflammatory reactions. Mutuations in IL-17F have been associated with Familial candidiasis 6 (CANDF6): a primary immunodeficiency disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida.
产品信息 格式 AlexaFluor®488 演示 Purified goat conjugate antibody in buffer containing PBS (pH 7.2) with up to 0.1% sodium azide and 0.2% (w/v) BSA. 应用 应用 Anti-IL-17F (human), Alexa Fluor® 488, clone Poly5166 Antibody is a highly specific goat polyclonal antibody & that targets IL-17 & has been tested in Flow Cytometry. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Immunogen information for this antibody is proprietary information. 克隆 Poly5166 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Goat 同种型 IgG 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - IL24
- IL17F
纯化方法 Affinity UniProt编号 - Q96PD4
产品使用声明 质量保证 The antibody was purified by affinity chromatography, and conjugated with AlexaFluor®488 under optimal conditions. The solution is free of unconjugated AlexaFluor®488 and unconjugated antibody. Alexa Fluor® 488 is a registered trademark of Molecular Probes, Inc. Alexa Fluor® 488 dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.
Flow Cytometry Analysis: 5 μL of this antibody detected IL-17F in one million PMA/ionomycin-stimulated human peripheral blood lymphocytes.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 The antibody solution should be stored undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.
包装信息 数量 100 tests
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