merck millipore,默克密理愽
  • merck millipore,默克密理博,475847,MIF Antagonist IV, RDR 03785 - Calbiochem

  • merck millipore,默克密理博,475847,MIF Antagonist IV, RDR 03785 - Calbiochem

    产品名称：MIF Antagonist IV, RDR 03785 - Calbiochem
    产品型号：475847
    The MIF Antagonist IV, RDR 03785 controls the biological activity of MIF. This small molecule/inhibitor is primarily used for Cell Structure applications.

    merck millipore,默克密理博,475847,MIF Antagonist IV, RDR 03785 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,475847,MIF Antagonist IV, RDR 03785 - Calbiochem

    重要规格表

    经验配方
    C₁₉H₁₈F₃NO₄
    描述
    概述 A cell-permeable morpholino-benzodioxol compound that inhibits MIF tautomerase activity (Ki and IC50 = 0.57 and 2.4 µM, respectively) via direct non-covalent MIF interaction (KD = 24.5 µM). RDR 03758 at 10 µM is shown to completely neutralize the overriding effect of 100 ng/ml MIF on the inhibition of LPS-stimulated TNF production by dexamethasone (Cat. No. 265005) in RAW 264.7 marcophage cultures.
    产品目录编号 475847
    品牌系列 Calbiochem®
    同义词 Macrophage Migration Inhibitory Factor Antagonist IV, 6-(Morpholino(4-(trifluoromethyl)phenyl)methyl)-1,3-benzodioxol-5-ol
    参考
    参考 Ouertatani-Sakouhi, H., et al. 2010. J. Biol. Chem. 285, 26581.
    产品信息
    形式 Cream solid
    Hill配方 C₁₉H₁₈F₃NO₄
    化学配方 C₁₉H₁₈F₃NO₄
    Molar Mass 381.4
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,475847,MIF Antagonist IV, RDR 03785 - Calbiochem

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