merck millipore,默克密理愽
  • merck millipore,默克密理博,MKI2MAG-94K,MILLIPLEX MAP Mouse Kidney Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

  • merck millipore,默克密理博,MKI2MAG-94K,MILLIPLEX MAP Mouse Kidney Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

    产品名称：MILLIPLEX MAP Mouse Kidney Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay
    产品型号：MKI2MAG-94K
    The analytes available for this multiplex kit are: Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, Osteopontin (OPN) (for urine samples) or Clusterin, Cystatin C, Lipocalin-2/NGAL, Osteopontin (OPN) (f More>>

    merck millipore,默克密理博,MKI2MAG-94K,MILLIPLEX MAP Mouse Kidney Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

  • 产品介绍
  • merck millipore,默克密理博,MKI2MAG-94K,MILLIPLEX MAP Mouse Kidney Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

    重要规格表

    可用的分析物 品种反应性 主要应用 检测方法
    Osteopontin (OPN), Clusterin, Cystatin C, EGF, Lipocalin-2/NGALMMplexLuminex xMAP
    描述
    产品目录编号 MKI2MAG-94K
    商名
    • MILLIPLEX
    描述 MILLIPLEX MAP Mouse Kidney Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay
    概述 The MILLIPLEX® MAP Mouse Kidney Injury Magnetic Bead Panel 2 contains all the components necessary to measure the following five biomarkers in any combination using Luminex® xMAP® technology: Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, Osteopontin (OPN). The kit uses a 96-well format, contains a lyophilized standard cocktail, two quality controls and can measure up to 38 urine samples in duplicate.
    背景信息 Maintenance of physiological balance in the body is attributed in part to normal kidney function. An altered kidney function due to injury, drug toxicity or kidney failure may be life threatening. There are multiple risk factors for kidney injury including age, hypertension, diabetes mellitus, heart failure and liver failure. On the other hand, drug induced damage to the kidney results from drug excretion. Traditional markers for assessing renal toxicity, such as blood urea nitrogen (BUN) and serum creatinine, are insensitive and non-specific. Although both are direct measurements of renal function, increases in serum concentrations of these biomarkers occur only after substantial renal injury. Specificity and earlier detection of kidney injury is vital. For improved detection of acute nephrotoxicity, a panel of novel urinary kidney biomarkers has been identified and validated for preclinical studies in relevant animal species.

    We provide valuable research assays to investigate multiple biomarkers of kidney injury in mouse urine samples using the Luminex xMAP® instrument platform.
    产品信息
    检测方法 Luminex xMAP
    配置 Design your multiplex kit by choosing analytes.
    精度（%）
    • Intra-Assay: < 10
    • Inter-assay: < 10
    板面类型 MAGNETIC Toxicity
    应用
    应用 The analytes available for this multiplex kit are: Clusterin, Cystatin C, EGF, Lipocalin-2/NGAL, Osteopontin (OPN) (for urine samples) or Clusterin, Cystatin C, Lipocalin-2/NGAL, Osteopontin (OPN) (for serum/plasma samples).
    主要应用
    • Multiplexing
    应用说明 • This is an overnight assay.
    • This assay requires 25 µL of 1:1,000 diluted urine sample per well in kit Assay Buffer (please dilute per protocol instructions).
    生物信息
    特异性 There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
    品种反应性 Mouse
    可用的分析物
    • Osteopontin (OPN)
    • Clusterin
    • Cystatin C
    • EGF
    • Lipocalin-2/NGAL
    化验面板 Everything you need in a single kit.
    交叉反应性 There was no or negligible cross-reactivity between the antibodies for an analyte and any of the other analytes within a panel.
    准确度
    • 90% - 99%
    理化信息
    灵敏度
    • Please see kit protocol for individual assay sensitivities.
    • 0.005 - 0.190 ng/mL (MinDC+2SD).
    稀释的线性 Contact technical support for this information.
    标准曲线范围
    • Osteopontin (OPN): 0.01 – 10 ng/mL
    • Clusterin: 0.2 – 250 ng/mL
    • Cystatin C: 0.05 – 50 ng/mL
    • EGF: 0.04 – 40 ng/mL
    • Lipocalin-2/NGAL: 0.005 – 5 ng/mL
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Recommended storage for kit components is 2 - 8°C.
    包装信息
    数量 96-well plate

    merck millipore,默克密理博,MKI2MAG-94K,MILLIPLEX MAP Mouse Kidney Injury Magnetic Bead Panel 2 - Toxicity Multiplex Assay

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