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merck millipore,默克密理博,266788,Diacylglycerol Kinase Inhibitor II - CAS 120166-69-0 - Calbiochem
产品名称：Diacylglycerol Kinase Inhibitor II - CAS 120166-69-0 - Calbiochem
产品型号：266788
The Diacylglycerol Kinase Inhibitor II, also referenced under CAS 120166-69-0, controls the biological activity of Diacylglycerol KInase. This small molecule/inhibitor is primarily used for Phosphoryl More>>
merck millipore,默克密理博,266788,Diacylglycerol Kinase Inhibitor II - CAS 120166-69-0 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₂₈H₂₅F₂N₃OS 120166-69-0 描述 概述 Inhibits diacylglycerol kinase in isolated platelet membranes (IC50 = 300 nM) and in intact platelets (IC50 = 120 nM) by binding to the catalytic domain. A more potent analog of diacylglycerol kinase inhibitor I (Cat. No. 266785). 产品目录编号 266788 品牌系列 Calbiochem®
同义词 R59949, 3-{2-[4-[bis-(4-Fluorophenyl)methylene]-1-piperidinyl]ethyl}-2,3-dihydro-2-thioxo-4(1H)quinazolinone, DGK Inhibitor II 参考 参考 Jiang, Y., et al. 2000. Biochem. Pharmacol. 59, 763.
Jones, D.R., et al. 1999. J. Biol. Chem. 274, 16846.
Rodriguez-Linares, B., et al. 1991. Biochem. Pharmacol. 41, 835.
de Chaffoy de Courcelles, D., et al. 1989. J. Biol. Chem. 264, 3274.产品信息 CAS号 120166-69-0 具有ATP竞争性 N 形式 White solid Hill配方 C₂₈H₂₅F₂N₃OS 化学配方 C₂₈H₂₅F₂N₃OS Molar Mass 489.6 可逆 N 结构配方图像 生物信息 主靶 Diacylglycerol Kinase 主靶IC50 300 nM and 120 nM against diacylglycerol kinase in isolated platelet membranes and in intact platelets, respectively 纯度 ≥98% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO 安全信息 R相 R: 36/37/38
Irritating to eyes, respiratory system and skin.S相 S: 26-36
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Irritant
储存 +15°C to +30°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot, flush with an inert gas and freeze at -20°C. Stock solutions are stable for up to 6 months at -20°C.
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