merck millipore,默克密理愽
  • merck millipore,默克密理博,420107,Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem

  • merck millipore,默克密理博,420107,Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem

    产品名称：Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem
    产品型号：420107
    A cell-permeable F-actin probe.

    merck millipore,默克密理博,420107,Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,420107,Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₃₆H₄₅BrN₄O₆102396-24-7
    描述
    概述 A cell-permeable F-actin probe. A cyclodepsipeptide with antifungal and antitumor properties. A potent inducer of actin polymerization and stabilization in vitro. Prevents activation of store-mediated Ca2+ entry into cells. It competes with Phalloidin (Cat. No. 516640) for actin binding (Kd = 15 nM) and enhances apoptosis induced by interleukin 2 (IL-2) deprivation. A 1 mM (50 µg/71 µl) solution of Jasplakinolide, Jaspis johnstoni (Cat. No. 420127) in DMSO is also available.
    产品目录编号 420107
    品牌系列 Calbiochem®
    参考
    参考 Rosado, J.A., et al. 2000. J. Biol. Chem. 275, 7527.
    Posey, S.C., and Bierer, B.E. 1999. J. Biol. Chem. 274, 4259.
    Senderowicz, A.M., et al. 1995. J. Natl. Cancer Inst. 87, 46.
    Bubb, M.R., et al. 1994. J. Biol. Chem. 269, 14869.
    Scott, V.R., et al. 1988. Antimicrob. Agents Chemother. 32, 1154.
    产品信息
    CAS号 102396-24-7
    具有ATP竞争性 N
    形式 Off-white solid
    Hill配方 C₃₆H₄₅BrN₄O₆
    化学配方 C₃₆H₄₅BrN₄O₆
    Molar Mass 709.7
    可逆 N
    结构配方图像
    生物信息
    主靶 Inducer of actin polymerization and stabilization in vitro
    主靶IC50 Kd = 15 nM for actin binding
    纯度 ≥95% by HPLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO
    安全信息
    R相 R: 20/21/22

    Harmful by inhalation, in contact with skin and if swallowed.
    S相 S: 36

    Wear suitable protective clothing.
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Harmful
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,420107,Jasplakinolide, Jaspis johnstoni - CAS 102396-24-7 - Calbiochem

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