merck millipore,默克密理愽
  • merck millipore,默克密理博,14-676,NLK Protein, active, 10 µg

  • merck millipore,默克密理博,14-676,NLK Protein, active, 10 µg

    产品名称：NLK Protein, active, 10 µg
    产品型号：14-676
    Active, N-terminal 6His-tagged, recombinant, human NLK, amino acids 121-end, for use in Kinase Assays.

    merck millipore,默克密理博,14-676,NLK Protein, active, 10 µg

  • 产品介绍
  • merck millipore,默克密理博,14-676,NLK Protein, active, 10 µg

    描述
    产品目录编号 14-676
    品牌系列 Upstate
    商名
    • Upstate
    描述 NLK Protein, active, 10 µg
    概述 N-terminal 6His-tagged, recombinant, human NLK, amino acids 121-end
    应用
    应用 Active, N-terminal 6His-tagged, recombinant, human NLK, amino acids 121-end, for use in Kinase Assays.
    主要应用
    • Kinase Assay
    生物信息
    来源 expressed by baculovirus in Sf21 cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_016231.4
    基因符号
    • LAK1
    • NLK
    • DKFZp761G1211
    • FLJ21033
    蛋白靶 NLK
    纯化方法 Ni2+/NTA-agarose
    靶子系列 CMGC
    UniProt编号
    • Q9UBE8
    UniProt汇总 FUNCTION: SwissProt: Q9UBE8 # Role in cell fate determination, required for differentiation of bone marrow stromal cells. Acts downstream of MAP3K7 and HIPK2 to negatively regulate the canonical Wnt/beta- catenin signaling pathway and the phosphorylation and destruction of the MYB transcription factor. May suppress a wide range of transcription factors by phosphorylation of the coactivator, CREBBP (By similarity).
    COFACTOR: Magnesium (By similarity).
    SIZE: 515 amino acids; 57048 Da
    SUBUNIT: Interacts with HIPK2 and MYB.
    SUBCELLULAR LOCATION: Nucleus (By similarity). Cytoplasm (By similarity). Note=Predominantly nuclear. A smaller fraction is cytoplasmic (By similarity).
    PTM: Dually phosphorylated on Thr-291 and Tyr-293, which activates the enzyme (By similarity).
    SIMILARITY: SwissProt: Q9UBE8 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. MAP kinase subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    质量保证 routinely evaluated by phosphorylation of myelin basic protein (Catalog # 13-104)
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 6 months at -70°C from date of shipment
    包装信息
    数量 10 µg

    merck millipore,默克密理博,14-676,NLK Protein, active, 10 µg

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