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merck millipore,默克密理博,SF-704,EZH2; Human, Cyanine 5, RNA Detection Probe,SmartFlare
产品名称：EZH2; Human, Cyanine 5, RNA Detection Probe, SmartFlare
产品型号：SF-704
Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare EZH2, Human, Cyanine 5, you can detect EZH2 RNA levels within your cells.
merck millipore,默克密理博,SF-704,EZH2; Human, Cyanine 5, RNA Detection Probe,SmartFlare
- 产品介绍
重要规格表
Entrez Gene Number Species Reactivity Species Reactivity Note NM_004456.4 H NM_152998.2, NM_001203247.1, NM_001203248.1, NM_001203249.1 描述 产品目录编号 SF-704 商名 - SmartFlare
描述 EZH2; Human, Cyanine 5, RNA Detection Probe | SmartFlare Alternate Names - KMT6
- ENX1
- EZH1
背景信息 With SmartFlare™ RNA Detection probes, you can detect RNA in LIVE CELLS with ease. With just an overnight incubation of EZH2; Human, Cyanine 5, RNA Detection Probe you can detect the presence of EZH2 within your cells.
Polycomb protein group complexes are responsible for the regulation of hundreds of genes in mammals and insects. These proteins are responsible for the assembly and packaging of chromatin and for the induction of methylation on Histone H3. EZH2 (enhancer of zeste homologue 2), also known as Enx1, is a member of the polycomb group of proteins and is involved in cell cycle regulation. EZH2 represses transcription via trimethylation of histone H3 on Lys27 (H3K27) as indicated by the fact that RNAi-mediated knockdown of EZH2 resulted in a loss of H3K27 trimethylation. The expression of this protein in human tumors is aggressive for hormone refractory prostate cancer. In breast cancer EZH2 expression was increased in malignant tumors and promoted anchorage independent and invasive growth in vitro. EZH2, also known as ENX-1, is ubiquitously expressed during early embryo genesis, and becomes restricted to the central and peripheral nervous systems and sites of fetal hematopoiesis during later development. In the adult, EZH2 is restricted to the spleen, testis and placenta. EZH2 and BMI-1 genes are co expressed in Reed-Sternberg cells of Hodgkin’s disease. Coexpression of BMI-1 and EZH2 is also associated with cycling cells and degree of malignancy in B-cell non-Hogkin’s lymphoma. EZH2 is involved in the progression of prostate cancer, and has been identified as a marker of aggressive breast cancer. Two transcript variants encoding distinct isoforms have been identified for this gene.产品信息 格式 Cyanine 5 演示 Lyophilized 应用 应用 Use SmartFlare RNA Detection probes to measure gene expression in live cells. With an overnight incubation of SmartFlare EZH2, Human, Cyanine 5, you can detect EZH2 RNA levels within your cells. 主要应用 - RNA Detection
生物信息 品种反应性 Human Species Reactivity Note NM_152998.2, NM_001203247.1, NM_001203248.1, NM_001203249.1 Entrez基因编号 - NM_004456.4
基因符号 - EZH2
产品使用声明 质量保证 SmartFlare Probes have been tested in a buffer system to detect the release of the fluorophore in the presence of a complimentary base pair sequence for each lot to confirm target specificity. SmartFlare Probes have also been tested in a cell model system and demonstrated increased fluorescence in cells expressing the target compared to a negative SmartFlare Scramble Control. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Store at 2–8°C in lyophilized format ONLY. Room temperature is required for reconstituted product. 包装信息 数量 250 reactions
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