merck millipore,默克密理愽
  • merck millipore,默克密理博,454586,NMDAR2C/2D Inhibitor, DQP-1105 - Calbiochem

  • merck millipore,默克密理博,454586,NMDAR2C/2D Inhibitor, DQP-1105 - Calbiochem

    产品名称：NMDAR2C/2D Inhibitor, DQP-1105 - Calbiochem
    产品型号：454586
    The NMDAR2C/2D Inhibitor, DQP-1105 controls the biological activity of NMDAR2C/2D. This small molecule/inhibitor is primarily used for Neuroscience applications.

    merck millipore,默克密理博,454586,NMDAR2C/2D Inhibitor, DQP-1105 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,454586,NMDAR2C/2D Inhibitor, DQP-1105 - Calbiochem

    重要规格表

    经验配方
    C₂₉H₂₄BrN₃O₄
    描述
    概述 A dihydroquinilone-pyrazoline NMDA antagonist, which is selective for NMDA receptors that are comprised of recombinant subunits GluN1/GluN2C (IC50 = 5.4 µM) and GluN1/GluN2D (2.2 µM) over GluN1/GluN2B (206 µM) and GluN1/ClucN2A (undetectable) in Xenopus oocytes. Similar selectivity is observed in whole-cell HEK patch-clamp assays with IC50 values for GluN2C and GluN2D that are at least 50-fold lower than those for recombinant GluN2A, GluN2B, GluA1, or GluK2-containing receptors. It inhibits NMDA by blocking a conformational change necessary for channel opening and is non-competitive with co-agonists, glutamate and glycine.
    产品目录编号 454586
    品牌系列 Calbiochem®
    同义词 DQP-1105, NMDA Antagonist IV
    参考
    参考 Acker, T., et al. 2011. Mol. Pharmacol. 80, 782.
    产品信息
    形式 Yellow-white solid
    Hill配方 C₂₉H₂₄BrN₃O₄
    化学配方 C₂₉H₂₄BrN₃O₄
    Molar Mass 558.42
    结构配方图像
    生物信息
    纯度 ≥97% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Regulatory Review
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,454586,NMDAR2C/2D Inhibitor, DQP-1105 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,GF430,HumanKine IL-6, Human Recombinant Xeno-Free
下一件merck millipore产品：merck millipore,默克密理博,AB2292,Anti-phospho GluR1 (Thr840) Antibody


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