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描述 概述 Recombinant, human, interleukin-6 expressed in E. coli. A prototypic pleiotrophic, pro-inflammatory cytokine that stimulates the production of acute phase proteins by hepatocytes. Also known to induce skeletal muscle protein breakdown. Induces growth and differentiation of B cells, T cells, and hepatocytes. Stimulates growth and inhibits constitutive, protein synthesis-independent apoptosis of murine B cell hybridoma 7TD1. IL-6 is produced by macrophages, endothelial cells, and activated T helper cells. Also considered as a potential marker of adipocyte differentiation. Human IL-6 is active on murine cells. 产品目录编号 407652 品牌系列 Calbiochem®
同义词 rhIL-6 参考 参考 Vicennati, V., et al. 2002. Int. J. Obes. Relat. Metab. Disord. 26, 9.
Vallieres, L., and Rivest, S. 1999. Endocrinology 140, 3890.
Goodman, M.N. 1994. Proc. Soc. Exp. Biol. Med. 205, 182.
Liu, J., et al. 1994. Cell Immunol. 155, 229.
Van Snick, J. 1990. Annu. Rev. Immunol. 8, 253.产品信息 形式 Lyophilized 配方 Carrier free. Molar Mass 20300 生物信息 生物活性 8-20 pg/ml as measured in a cell proliferation assay with a factor-dependent murine plasmacytoma cell line, B9. 纯度 ≥95% by SDS-PAGE 理化信息 污染物 Endotoxin: ≤1.0 EU/µg IL-6 溶解度 100 mM Acetic Acid 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 ≤ -70°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
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