• merck millipore,默克密理博,MAB1612,Anti-Cytokeratin Epithelial Antibody, clone AE1
  • merck millipore,默克密理博,MAB1612,Anti-Cytokeratin Epithelial Antibody, clone AE1

    产品名称:Anti-Cytokeratin Epithelial Antibody, clone AE1
    产品型号:MAB1612
    This Anti-Cytokeratin Epithelial Antibody, clone AE1 is validated for use in IH(P) for the detection of Cytokeratin Epithelial.

    merck millipore,默克密理博,MAB1612,Anti-Cytokeratin Epithelial Antibody, clone AE1

  • 产品介绍
  • merck millipore,默克密理博,MAB1612,Anti-Cytokeratin Epithelial Antibody, clone AE1

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Rb, B, Ch, H, M, RIH(P)MPurifiedMonoclonal Antibody
    描述
    产品目录编号 MAB1612
    Replaces 04-588
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Cytokeratin Epithelial Antibody, clone AE1
    产品信息
    格式 Purified
    演示 Liquid in 0.05M Borate Buffered Saline, 0.15M NaCl, 0.09% Sodium Azide, pH8.2.
    应用
    应用 This Anti-Cytokeratin Epithelial Antibody, clone AE1 is validated for use in IH(P) for the detection of Cytokeratin Epithelial.
    主要应用
    • Immunohistochemistry (Paraffin)
    应用说明 Immunohistochemistry on unfixed frozen sections and formalin-fixed paraffin embedded tissues. Antigen retrieval is recommended. HEIR or protease treatment can be used.

    Western Blotting: AE1 recognizes LMW cytokeratins from the acidic subfamily including: Clone AE1 recognises the 56.5, 50, 50', 48 and 40kD human cytokeratins of the acidic subfamily.

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Human epidermal keratin
    克隆 AE1
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Recognizes most of the acidic (Type I) keratins. It is broadly reactive and stains positively almost all epithelia and their neoplasms. MAB1612 produces heterogeneous staining within a given epithelium; the detailed staining pattern varies depending on the differentiated and/or growth state of individual cells.
    同种型 IgG
    品种反应性 RabbitBovineChickenHumanMouseRat
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_002273.2
    基因符号
    • CARD2
    • KRT8
    • KO
    • K8
    • CYK8
    • Keratin-8
    • CK-8
    • Cytokeratin-8
    • K2C8
    • CK8
    UniProt编号
    • P05787
    UniProt汇总 FUNCTION: SwissProt: P05787 # Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.
    SIZE: 483 amino acids; 53704 Da
    SUBUNIT: Heterotetramer of two type I and two type II keratins. keratin-8 associates with keratin-18. Associates with KRT20. Interacts with HCV core protein and PNN. When associated with KRT19, interacts with DMD. Interacts with TCHP.
    SUBCELLULAR LOCATION: Cytoplasm.
    TISSUE SPECIFICITY: Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.
    PTM: Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
    DISEASE:SwissProt: P05787 # Defects in KRT8 are a cause of cryptogenic cirrhosis [MIM:215600].
    SIMILARITY: SwissProt: P05787 ## Belongs to the intermediate filament family.
    MISCELLANEOUS: There are two types of cytoskeletal and microfibrillar keratin: I (acidic; 40-55 kDa) and II (neutral to basic; 56-70 kDa).
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at 2-8°C in undiluted aliquots for up to 6 months.
    包装信息
    数量 500 µg

    merck millipore,默克密理博,MAB1612,Anti-Cytokeratin Epithelial Antibody, clone AE1

上一件merck millipore产品:merck millipore,默克密理博,ABE573,Anti-Zeb2 Antibody
下一件merck millipore产品:merck millipore,默克密理博,XX6504704,溶剂分液瓶



whatman,沃特曼,nalgene,耐洁,merck millipore,默克密理愽,sartorius,赛多利斯,pall,颇尔
thermo fisher,赛默飞世尔,GE,MN,macherey-nagel,advantec,wheaton,brand,普兰德,welch,airtech


上海羽令过滤器材有限公司版权所有 Copyright ©  www.yl-guolv.com  Powered by 羽令集团—信息技术部