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merck millipore,默克密理博,407625,STAT3 Inhibitor XVI - Calbiochem
产品名称：STAT3 Inhibitor XVI - Calbiochem
产品型号：407625
The STAT3 Inhibitor XVI controls the biological activity of STAT3. This small molecule/inhibitor is primarily used for Cancer applications.
merck millipore,默克密理博,407625,STAT3 Inhibitor XVI - Calbiochem
- 产品介绍
重要规格表
经验配方 C₂₁H₂₂N₂O₃S₃ 描述 概述 A cell-permeable, arylsulphonamidyl thiophene amide that is shown to reduce IL-6-induced STAT3 transcriptional activity (EC50 = 15 µM) in a luciferase reporter assay, in HeLa cells. It selectively inhibits STAT3, but not STAT1, phosphorylation following IL-6 stimulation in both HeLa and MDA-MB-231 breast cancer cells at concentrations of 10-30 µ:M and 30-100 µM, respectively. Following IL-6 stimulation, it suppresses the cell viability of STAT3-dependent cancer cells by 40% compared with that of STAT3-null cancer cells at the low micromolar level. 产品目录编号 407625 品牌系列 Calbiochem®
同义词 IL-6 Inhibitor 参考 参考 Zinzalla, G., et al. 2010. Bioorg Med Chem Lett 20, 7029. 产品信息 形式 Grey solid Hill配方 C₂₁H₂₂N₂O₃S₃ 化学配方 C₂₁H₂₂N₂O₃S₃ Molar Mass 446.08 结构配方图像 生物信息 纯度 ≥98% by HPLC 理化信息 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Regulatory Review
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品：merck millipore,默克密理博,428018,Sodium n-Dodecyl Sulfate, 20% Solution (w/v) - CAS 151-21-3 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,385570,Heat Shock Factor 1 Inhibitor, KRIBB11 - Calbiochem
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