merck millipore,默克密理愽
  • merck millipore,默克密理博,397100,HNMPA-(AM)₃ - CAS 120944-03-8 - Calbiochem

  • merck millipore,默克密理博,397100,HNMPA-(AM)₃ - CAS 120944-03-8 - Calbiochem

    产品名称：HNMPA-(AM)₃ - CAS 120944-03-8 - Calbiochem
    产品型号：397100
    A cell-permeable analog of HNMPA that yields the parent compound upon cleavage by cytosolic esterases.

    merck millipore,默克密理博,397100,HNMPA-(AM)₃ - CAS 120944-03-8 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,397100,HNMPA-(AM)₃ - CAS 120944-03-8 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₂₀H₂₃O₁₀P120944-03-8
    描述
    概述 A cell-permeable analog of HNMPA that yields the parent compound upon cleavage by cytosolic esterases. Inhibits insulin receptor tyrosine kinase (IC50 = 100 µM) and insulin-stimulated glucose oxidation in isolated rat adipocytes (IC50 = 10 µM). Also reported to inhibit tyrosine autophosphorylation of the human insulin receptor (IC50 = 200 µM).
    产品目录编号 397100
    品牌系列 Calbiochem®
    同义词 Hydroxy-2-naphthalenylmethylphosphonic Acid Trisacetoxymethyl Ester, Pro-drug II
    参考
    参考 Baltensperger, K., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 7885.
    Saperstein, R., et al. 1989. Biochemistry 28, 5694.
    产品信息
    CAS号 120944-03-8
    具有ATP竞争性 N
    形式 Colorless oil
    Hill配方 C₂₀H₂₃O₁₀P
    化学配方 C₂₀H₂₃O₁₀P
    Molar Mass 454.4
    可逆 N
    结构配方图像
    生物信息
    主靶 tyrosine kinase
    主靶IC50 100 µM and 10 µM against insulin receptor tyrosine kinase and insulin-stimulated glucose oxidation in isolated rat adipocytes, respectively
    纯度 ≥98% by TLC
    理化信息
    细胞可渗透 Y
    溶解度 DMSO or EtOH
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 -20°C
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

    merck millipore,默克密理博,397100,HNMPA-(AM)₃ - CAS 120944-03-8 - Calbiochem

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