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merck millipore,默克密理博,05-1361,Anti-PURA Antibody, clone 2B7
产品名称:Anti-PURA Antibody, clone 2B7
产品型号:05-1361
Use Anti-PURA Antibody, clone 2B7 (mouse monoclonal antibody) validated in WB to detect PURA also known as transcriptional activator protein PUR-alpha, Purine-rich single-str&ed DNA-binding protein al More>>
merck millipore,默克密理博,05-1361,Anti-PURA Antibody, clone 2B7
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H, M WB M Purified Monoclonal Antibody 描述 产品目录编号 05-1361 描述 Anti-PURA Antibody, clone 2B7 Alternate Names - Purine-rich single-stranded DNA-binding protein alpha
- transcriptional activator protein PUR-alpha
- purine-rich element binding protein A
背景信息 Purine-rich element binding protein A, also known as PURA, is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. 产品信息 格式 Purified 控制 - A549 cell lysate
演示 Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide. 应用 应用 Use Anti-PURA Antibody, clone 2B7 (mouse monoclonal antibody) validated in WB to detect PURA also known as transcriptional activator protein PUR-alpha, Purine-rich single-str&ed DNA-binding protein alpha . 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to PURA. 克隆 2B7 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody detects PURA. 同种型 IgG2aκ 品种反应性 RatHumanMouse Species Reactivity Note Human, mouse and rat. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_005850.1
Entrez基因汇总 This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq].
基因符号 - PURALPHA
- PUR-ALPHA
- PUR1
纯化方法 Protein G purfied UniProt编号 - Q00577
UniProt汇总 FUNCTION: This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene. May play a role in the initiation of DNA replication and in recombination.
SUBUNIT STRUCTURE: Homodimer, heterodimer with PURB and heterotrimer with PURB and YBX1/Y-box protein 1 By similarity.
SUBCELLULAR LOCATION: Nucleus.
SEQUENCE SIMILARITIES: Belongs to the PUR DNA-binding protein family.
产品使用声明 质量保证 Evaluated by western blot on A549 cell lysate.
Western Blot Analysis: 0.5-2 µg/mL of this antibody detected PURA in A549 cell lysate.
使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8ºC from date of receipt. 包装信息 数量 100 µg
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