• merck millipore,默克密理博,371709,GPR109b Agonist - CAS 306935-41-1 - Calbiochem
  • merck millipore,默克密理博,371709,GPR109b Agonist - CAS 306935-41-1 - Calbiochem

    产品名称:GPR109b Agonist - CAS 306935-41-1 - Calbiochem
    产品型号:371709
    The GPR109b Agonist, also referenced under CAS 306935-41-1, controls the biological activity of GPR109b. This small molecule/inhibitor is primarily used for Activators/Inducers applications.

    merck millipore,默克密理博,371709,GPR109b Agonist - CAS 306935-41-1 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,371709,GPR109b Agonist - CAS 306935-41-1 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₀H₁₁N₃O₂306935-41-1
    描述
    概述 A cell-permeable Niacin (Cat. No. 481918) triazolo derivative that acts as a potent and selective agonist toward the human orphan G-protein-coupled receptor GPR109b/HM74, but not GPR109a/HM74A or β-adrenergic receptor. Effectively inhibits cAMP elevation induced by forskolin (5 µM, Cat. No. 344270) and isoproterenol (1 µM, Cat. No. 420355), respectively, in GPR109b-expressing CHO cells (EC50 = 400 nM) and freshly isolated human adipocytes (EC50 about 1 µM).
    产品目录编号 371709
    品牌系列 Calbiochem®
    同义词 1-(iso-Propyl)-1H-benzotriazole-5-carboxylic acid
    参考
    参考 Semple, G., et al. 2006. J. Med. Chem. 49, 1227.
    产品信息
    CAS号 306935-41-1
    形式 Light brown solid
    Hill配方 C₁₀H₁₁N₃O₂
    化学配方 C₁₀H₁₁N₃O₂
    Molar Mass 205.2
    结构配方图像
    生物信息
    纯度 ≥98% by HPLC
    理化信息
    溶解度 DMSO or EtOH
    安全信息
    R相 R: 36/37/38

    Irritating to eyes, respiratory system and skin.
    S相 S: 26-36-45

    In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
    Wear suitable protective clothing.
    In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Irritant
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,371709,GPR109b Agonist - CAS 306935-41-1 - Calbiochem

上一件merck millipore产品:merck millipore,默克密理博,344852,Fumonisin B₂, Fusarium moniliforme - CAS 116355-84-1 - Calbiochem
下一件merck millipore产品:merck millipore,默克密理博,06-138,Anti-Cyclin A Antibody



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