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描述 概述 Native factor I from human serum. Glycoprotein composed of two non-identical disulfide-bonded subunits of M.W. of 50 kDa (α) and 38 kDa (β). Present in normal human serum at about 34 µg/ml. A serine protease that requires protein cofactor in order to effect substrate cleavage. Thus, either Factor H or Factor I mediates cleavage of C3b. C4-binding protein or complement receptor CR1 can function as the cofactor required for Factor I-mediated cleavage of C4b. 产品目录编号 341280 品牌系列 Calbiochem®
同义词 C3b/C4b Inactivator 参考 参考 Solol-Celigny, P., et al. 1982. Clin. Exp. Immunol. 47, 197.
Pangburn, M.K., et al. 1977. J. Exp. Med. 146, 257.产品信息 形式 Liquid 配方 In PBS, pH 7.2. Molar Mass 88000 生物信息 纯度 ≥95% by SDS-PAGE 来源 Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. 浓缩标签 Please refer to vial label for lot-specific concentration
理化信息 污染物 IgG, IgA, IgM, Factor H, Factor B, Factor P, C3, C4, or albumin: ≤trace amounts 储存和货运信息 货运代码 Dry Ice Only
毒性 Standard Handling
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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