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品种反应性 主要应用 宿主 格式 抗体类型 M, H WB, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABS523 描述 Anti-Lipin-1 Antibody Alternate Names - Lipin-1
- Phosphatidate phosphatase LPIN1
背景信息 Lipin-1 is also called Phosphatidate phosphatase LPIN1. Lipin-1 controls the metabolism of fatty acids, acts as a magnesium-dependent phosphatidate phosphatase enzyme, as well as a nuclear transcriptional coactivator that modulates lipid metabolism gene expression. Lipin-1 involved in adipocyte differentiation, and is also potentially involved in mitochondrial fission. Lipin-1 is specifically expressed in skeletal muscle, and is also abundant in adipose tissue. Lipin-1 defects can cause autosomal recessive acute recurrent myoglobinuria (ARARM). 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide with 50% glycerol. 应用 应用 Anti-Lipin-1 Antibody is an antibody against Lipin-1 for use in IHC, western blotting & IP. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Lipin-1 in human cardiac myocytes and human skeletal muscle myocytes tissue.
Western Blotting Analysis: A representative lot detected Lipin-1 in mouse adipose tissue lysate (Mayurranjan, S., et al. (2013). PNAS. 110(2):642-647).
Immunoprecipitation Analysis: A representative lot immunoprecipitated Lipin-1 in adipose tissue lysate (Mayurranjan, S., et al. (2013). PNAS. 110(2):642-647).生物信息 免疫原品种 linear peptide corresponding to human Lipin-1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 MouseHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001248356
基因符号 - KIAA0188
- LPIN1
纯化方法 Affinity purified UniProt编号 - Q14693
产品使用声明 质量保证 Evaluated by Western Blotting in mouse hepatocytes overexpressing lipin1 cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected Lipin-1 in 10 µg of mouse hepatocytes overexpressing lipin1 cell lysate (lysate from the laboratory of Brian Finck, Washington University, St. Louis).使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 100 µg
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