- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M WB M Purified Monoclonal Antibody 描述 产品目录编号 MAB4386 描述 Anti-NDP52 Antibody, clone 10F1.2 Alternate Names - nuclear domain 10 protein
- Antigen nuclear dot 52 kDa protein
- Nuclear domain 10 protein 52
- Nuclear domain 10 protein NDP52
- Nuclear dot protein 52
- calcium binding and coiled-coil domain 2
背景信息 NDP52, also known as Nuclear Domain 10 protein NDP52 or Calcium-binding and coiled-coil domain-containing protein 2, is a novel protein of the ND10 (nuclear domain 10). It is part of a complex consisting of CALCOCO2, TAX1BP1 and MYO6 and interacts with GEMIN4. NDP52 expression is limited to the pluripotent cells of the early embryo and the germline. It is also expressed in blastocysts, epiblasts and purified primordial germ cells. Recent findings show that NDP52 co-localizes with the ND10 protein PML and can be redistributed upon viral infection and interferon treatment, suggesting that ND10 proteins play an important role in the viral life cycle. Furthermore, NPD252 may play a role in ruffle formation and actin cytoskeleton organization. 产品信息 格式 Purified 控制 - Mouse embryonic stem cell lysate
演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide. 应用 应用 This Anti-NDP52 Antibody, clone 10F1.2 is validated for use in WB for the detection of NDP52. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged recombinant protein corresponding to mouse NDP52. 表位 Unknown 克隆 10F1.2 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Mouse 特异性 This antibody recognizes NDP52. 同种型 IgG1κ 品种反应性 Mouse Species Reactivity Note Proven to react with mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_001093647.1
基因符号 - CALCOCO2
- NDP52
纯化方法 Protein G purfied UniProt编号 - A2A6M5
UniProt汇总 FUNCTION: May play a role in ruffle formation and actin cytoskeleton organization. Seems to negatively regulate constitutive secretion By similarity.
SUBUNIT STRUCTURE: Part of a complex consisting of CALCOCO2, TAX1BP1 and MYO6. Interacts with GEMIN4 By similarity.
SUBCELLULAR LOCATION: Cytoplasm › perinuclear region By similarity. Golgi apparatus By similarity. Cytoplasm › cytoskeleton By similarity.
DEVELOPMENTAL STAGE: Expression is limited to the pluripotent cells of the early embryo and the germline. Expressed in blastocysts, epiblasts and purified primordial germ cells.
SEQUENCE SIMLARITIES: Belongs to the CALCOCO family.
SEQUENCE CAUTION: The sequence BAE38997.1 differs from that shown. Reason: Frameshift at position 193.产品使用声明 质量保证 Evaluated by Western Blot in mouse embryonic stem cell lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected NDP52 in 10 µg of mouse embryonic stem cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,07-1799,Anti-NCoA-2 Antibody
下一件merck millipore产品：merck millipore,默克密理博,ABC833,Anti-TRIM25 Antibody
相关产品
merck millipore,默克密理博,MABS10,Anti-NEDD8-conjugating enzyme Ubc12 Antibody, clone 9H1.1
merck millipore,默克密理博,0500-5120,InCyte Software for guava easyCyte Systems
merck millipore,默克密理博,328000,ERK Activation Inhibitor Peptide I, Cell-Permeable - Calbiochem
merck millipore,默克密理博,3150-OP,OmniPur Chloroform
merck millipore,默克密理博,07-1799,Anti-NCoA-2 Antibody
merck millipore,默克密理博,ABC833,Anti-TRIM25 Antibody
merck millipore,默克密理博,341280,Factor I, Human
merck millipore,默克密理博,MABE13,Anti-phospho Histone H3 (Ser28) Antibody, clone E191, rabbit monoclonal
merck millipore,默克密理博,04-205,Anti-CENP-A Antibody, clone EP800Y, rabbit monoclonal