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经验配方 C₁₆H₁₄ClMnN₂O₂ 描述 概述 A synthetic salen-manganese complex with high superoxide dismutase (SOD) and catalase-mimic activities, and oxyradical scavenging activities. Shown to have protective effects in numerous models for disease processes associated with oxidative stress, including inflammation, cardiovascular diseases, acute critical illness, autoimmune diseases, and neurological disorders. Useful in preventing cardiac damage caused by ischemic reperfusion. Also prevents β-amyloid peptide (Aβ)-induced free radical formation and lipid peroxidation. Imparts protection against Aβ40 and Aβ42 toxicity in hippocampal cultures. 产品目录编号 341209 品牌系列 Calbiochem®
参考 参考 Colparet, E. E. and Lefebure, R. A. 2000. Br. J. Pharmacol. 130, 359.
Brandier, C., et al. 1997. J. Vasc. Res. 34, 49.
Doctrow, S.R., et al. 1997. Adv. Pharmacol. 38, 247.
Bruce, A.J., et al. 1996. Proc. Natl. Acad. Sci. USA 93, 2312.
Pucheu, S., et al. 1996. Cardiovasc. Drug Ther. 10, 331.
Baudry, M., et al. 1993. Biochem. Biophys. Res. Commun. 192, 964.产品信息 具有ATP竞争性 N 声明 Not available for sale in Africa, Australia, Great Britain, Europe, Latvia, New Zealand, and the United States. 形式 Dark brown solid Hill配方 C₁₆H₁₄ClMnN₂O₂ 化学配方 C₁₆H₁₄ClMnN₂O₂ Molar Mass 356.7 可逆 N 结构配方图像 生物信息 主靶 Superoxide dismutase (SOD) and catalase-mimic activities, and oxyradical scavenging activities 纯度 ≥90% by elemental analysis 理化信息 细胞可渗透 N 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 weeks at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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