merck millipore,默克密理博,MABN358,Anti-NB thymosin beta (TMSB15A Antibody), Clone 4A6.3

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	IH(P)	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABN358
描述	Anti-NB thymosin beta (TMSB15A Antibody), Clone 4A6.3
Alternate Names	Thymosin-like protein 8 Thymosin beta-15A NB thymosin beta
背景信息	TMSB15A protein is a key regulator of the cytoskeleton organization and polymerization, and it thus plays a role in cell migration, proliferation and cancer. TMSB15A does this because TMSB15A binds to and sequesters actin monomers and limits action polymerization. TMSB15A is differentially expressed in many tissues and cancer cell lines. Because of differential expression in certain cancers, for instance in triple negative breast cancer but not colon cancer, TMSB15A is being examined as a histochemical marker for measuring the effectiveness of cancer therapy on cancer. TMSB15A is also important in the nervous system and brain diseases. Notably, TMSB15A expression is increased upon brain stress and surprisingly TMSB15A localization differs depending upon the type of stress used and neuronal cell type. Because of its interaction with actin, TMSB15A is localized to the cytoplasm most of time, however, in the brain and when cells are placed under various stresses, TMSB15A can be translocated to the brain to perform yet unknown functions as well.

产品信息
格式	Purified
演示	Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

应用
应用	This Anti-NB thymosin beta (TMSB15A Antibody), Clone 4A6.3 is validated for use in Immunohistochemistry (Paraffin) for the detection of NB thymosin beta (TMSB15A).
主要应用	Immunohistochemistry (Paraffin)
应用说明	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected TMSB15A in human thalamic and human brain cancer tissues.

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to Human TMSB15A.
克隆	4A6.3
浓缩	Please refer to lot specific datasheet.
宿主	Mouse
同种型	IgMκ
品种反应性	Human
Species Reactivity Note	Human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_068832
基因符号	TMSNB TMSB15A TMSL8
纯化方法	Purified by ion-exchange chromatography
UniProt编号	P0CG34

产品使用声明
质量保证	Evaluated by Immunohistochemistry in human cerebral cortex tissue. Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected TMSB15A in human cerebral cortex tissue
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,MABN358,Anti-NB thymosin beta (TMSB15A Antibody), Clone 4A6.3

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