merck millipore,默克密理愽
  • merck millipore,默克密理博,33-017,PI 3-Kinase HTRF™ Assay; 1920 wells

  • merck millipore,默克密理博,33-017,PI 3-Kinase HTRF™ Assay; 1920 wells

    产品名称：PI 3-Kinase HTRF™ Assay; 1920 wells
    产品型号：33-017
    The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 5 pl More>>

    merck millipore,默克密理博,33-017,PI 3-Kinase HTRF™ Assay; 1920 wells

  • 产品介绍
  • merck millipore,默克密理博,33-017,PI 3-Kinase HTRF™ Assay; 1920 wells

    描述
    产品目录编号 33-017
    品牌系列 Upstate
    商名
    • Upstate
    • HTRF
    描述 PI 3-Kinase HTRF™ Assay; 1920 wells
    产品信息
    部件
    • DM C Detection Reagent
    • 4X Reaction Buffer
    • PIP2 (Substrate; 1mM stock)
    • Stop Reagent A
    • Stop Reagent B
    • DM A Detection Reagent
    • DM B Detection Reagent
    检测方法 HTRF
    应用
    应用 The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 5 plates.
    主要应用
    • Kinase Assay
    生物信息
    品种反应性 MouseHuman
    可用的分析物
    • PI 3-Kinase
    Entrez基因编号
    • NM_006218.2
    Entrez基因汇总 Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns(4,5)P2. This gene has been found to be oncogenic and has been implicated in cervical cancers.
    基因符号
    • p110-alpha
    • PIK3CA
    • MGC142163
    • PI3K
    • MGC142161
    靶子系列 PI3K/PI4K
    UniProt编号
    • P42336
    UniProt汇总 FUNCTION: SwissProt: P42336 # Phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2 with a preference for PtdIns(4,5)P2.
    SIZE: 1068 amino acids; 124284 Da
    SUBUNIT: Heterodimer of a p110 (catalytic) and a p85 (regulatory) subunit. Binds to IRS1 in nuclear extracts. Interacts with RUFY3 (By similarity).
    DISEASE: SwissProt: P42336 # Defects in PIK3CA are associated with colorectal cancer (CRC) [MIM:114500]. & Defects in PIK3CA are associated with breast cancer [MIM:114480]. & Defects in PIK3CA are associated with epithelial ovarian cancer (EOC) [MIM:604370].
    SIMILARITY: SwissProt: P42336 ## Belongs to the PI3/PI4-kinase family. & Contains 1 C2 domain. & Contains 1 PI3K/PI4K domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    包装信息
    数量 5 plates
    包装 Kit capacity: 1920 wells

    merck millipore,默克密理博,33-017,PI 3-Kinase HTRF™ Assay; 1920 wells

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