merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL168F,Anti-CD36 Antibody, clone SM-phi, FITC conjugated

  • merck millipore,默克密理博,CBL168F,Anti-CD36 Antibody, clone SM-phi, FITC conjugated

    产品名称：Anti-CD36 Antibody, clone SM-phi, FITC conjugated
    产品型号：CBL168F
    This Anti-CD36 Antibody, clone SM-phi, FITC conjugated is validated for use in FC, IH for the detection of CD36d.

    merck millipore,默克密理博,CBL168F,Anti-CD36 Antibody, clone SM-phi, FITC conjugated

  • 产品介绍
  • merck millipore,默克密理博,CBL168F,Anti-CD36 Antibody, clone SM-phi, FITC conjugated

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, FCMFITCMonoclonal Antibody
    描述
    产品目录编号 CBL168F
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-CD36 Antibody, clone SM-phi, FITC conjugated
    Alternate Names
    • Platelet Glycoprotein IV
    产品信息
    格式 FITC
    演示 The monoclonal was purified by affinity chromatography and gel filtration prior to conjugation. The conjugate is supplied in 1.0 ml of phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.
    应用
    应用 This Anti-CD36 Antibody, clone SM-phi, FITC conjugated is validated for use in FC, IH for the detection of CD36d.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    应用说明 Studies of platelet and monocyte receptor for thrombospondin

    Studies of platelet collagen adhesion receptor

    Flow cytometry

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Human tonsil cells and peripheral blood mononuclear cells
    克隆 SM-phi
    宿主 Mouse
    特异性 This antibody recognizes the 90 kDa single chain membrane glycoprotein (GPIIIb) that is found on monocytes/macrophages and platelets. FUSION PARTNER: NS1 myeloma cell line
    同种型 IgM
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001001548.1
    • NM_000072.2
    • NM_001001547.1
    Entrez基因汇总 The protein encoded by this gene is the fourth major glycoprotein of the platelet surface and serves as a receptor for thrombospondin in platelets and various cell lines. Since thrombospondins are widely distributed proteins involved in a variety of adhesive processes, this protein may have important functions as a cell adhesion molecule. It binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. It directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes and it binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport. Mutations in this gene cause platelet glycoprotein deficiency. Three alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
    基因符号
    • GPIIIB
    • CD36
    • PAS-4
    • GPIV
    • FAT
    • CHDS7
    • GP3B
    • SCARB3
    • PASIV
    • GP4
    UniProt编号
    • P16671
    UniProt汇总 FUNCTION: SwissProt: P16671 # Seems to have numerous potential physiological functions. Binds to collagen, thrombospondin, anionic phospholipids and oxidized LDL. May function as a cell adhesion molecule. Directly mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Binds long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport.
    SIZE: 472 amino acids; 53053 Da
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    PTM: N-glycosylated and O-glycosylated with a ratio of 2:1.
    DISEASE: SwissProt: P16671 # Defects in CD36 are the cause of platelet glycoprotein IV deficiency [MIM:608404]; also known as CD36 deficiency. Platelet glycoprotein IV deficiency can be divided into 2 subgroups. The type I phenotype is characterized by platelets and monocytes/macrophages exhibiting complete CD36 deficiency. The type II phenotype lacks the surface expression of CD36 in platelets, but expression in monocytes/macrophages is near normal. & Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7) [MIM:610938].
    SIMILARITY: SwissProt: P16671 ## Belongs to the CD36 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C for up to one year.
    包装信息
    数量 100 assays

    merck millipore,默克密理博,CBL168F,Anti-CD36 Antibody, clone SM-phi, FITC conjugated

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