merck millipore,默克密理愽
  • merck millipore,默克密理博,250401,Cytoplasmic Dynein Inhibitor, Ciliobrevin D - Calbiochem

  • merck millipore,默克密理博,250401,Cytoplasmic Dynein Inhibitor, Ciliobrevin D - Calbiochem

    产品名称：Cytoplasmic Dynein Inhibitor, Ciliobrevin D - Calbiochem
    产品型号：250401
    The Cytoplasmic Dynein Inhibitor, Ciliobrevin D controls the biological activity of Cytoplasmic Dynein. This small molecule/inhibitor is primarily used for Cell Signaling applications.

    merck millipore,默克密理博,250401,Cytoplasmic Dynein Inhibitor, Ciliobrevin D - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,250401,Cytoplasmic Dynein Inhibitor, Ciliobrevin D - Calbiochem

    重要规格表

    经验配方
    C₁₇H₈Cl₃N₃O₂
    描述
    概述 A cell-permeable benzoyl dihydroquinazolinone derivative that acts as a reversible and specific blocker of AAA+ ATPase motor cytoplasmic dynein and disrupts spindle pole focusing, cold-stable microtubule formation, kinetochore-microtubule attachment, and melanosome aggregation in a dose-dependent manner (~10 to 40 µM). Shown to perturb protein trafficking within the primary cilia and cause a significant increase in intraflagellar transport protein 88 (IFT88) levels at the distal tip of primary cilia. Reported to disrupt primary cilium-dependent Gli regulation and block Hedgehog signaling.
    产品目录编号 250401
    品牌系列 Calbiochem®
    同义词 2-(7-chloro-4-oxo-3,4-dihydroquinazolin-2(1H)-ylidene)-3-(2,4-dichlorophenyl)-3-oxopropanenitrile, AAA+ ATPase motor cytoplasmic dynein inhibitor
    参考
    参考 Firestone, A., et al. 2012. Nature.
    484, 125.
    产品信息
    形式 Orange powder
    Hill配方 C₁₇H₈Cl₃N₃O₂
    化学配方 C₁₇H₈Cl₃N₃O₂
    Molar Mass 392.6
    结构配方图像
    生物信息
    纯度 ≥99% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,250401,Cytoplasmic Dynein Inhibitor, Ciliobrevin D - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,AB3841,Anti-Connexin 43 Antibody, phospho-specific (Ser368)
下一件merck millipore产品：merck millipore,默克密理博,ABN353,Anti-SAPAP2 Antibody


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