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品种反应性 主要应用 宿主 格式 抗体类型 R, B, H, M WB, IHC Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB5610 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-GABA A Receptor α6 Antibody 产品信息 格式 Affinity Purified 控制 - Brain tissue
演示 Affinity Purified immunoglobulin. Liquid in PBS with 0.02% sodium azide as a preservative. 应用 应用 Detect GABA A Receptor α6 using this Anti-GABA A Receptor α6 Antibody validated for use in IH, IP & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Immunoblot: 0.5-1.0 μg/mL
Immunohistochemistry: 0.5-1.0 μg/mL on paraformaldehyde fixed tissue.
Immunoprecipitation: 0.5-1.0 μg/mL
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide corresponding to amino acids 1-16 of bovine GABA(A) Receptor alpha6 subunit. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes GABA(A) Receptor alpha6 subunit. The GABA(A) receptor alpha6 subunit is expressed in cerebellar granule cells at ~ post-natal day 14 and is an excellent marker of mature cerebellar granule cells. 品种反应性 RatBovineHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000811.2
Entrez基因汇总 GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. 基因符号 - MGC116903
- GABRA6
- MGC116904
- GABA
纯化方法 Immunoaffinity purified UniProt编号 - Q16445
UniProt汇总 FUNCTION: SwissProt: Q16445 # GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
SIZE: 453 amino acids; 51024 Da
SUBUNIT: Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.
SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: Q16445 ## Belongs to the ligand-gated ionic channel (TC 1.A.9) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 1 year at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 100 µg
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