merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5869P,Anti-Dynamitin (p50) Antibody, a.a. 1-83

  • merck millipore,默克密理博,AB5869P,Anti-Dynamitin (p50) Antibody, a.a. 1-83

    产品名称：Anti-Dynamitin (p50) Antibody, a.a. 1-83
    产品型号：AB5869P
    Anti-Dynamitin (p50) Antibody, a.a. 1-83 detects level of Dynamitin (p50) & has been published & validated for use in WB.

    merck millipore,默克密理博,AB5869P,Anti-Dynamitin (p50) Antibody, a.a. 1-83

  • 产品介绍
  • merck millipore,默克密理博,AB5869P,Anti-Dynamitin (p50) Antibody, a.a. 1-83

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Rb, H, M, RWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5869P
    Replaces AB5865P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Dynamitin (p50) Antibody, a.a. 1-83
    Alternate Names
    • Dynactin 2
    • Dynactin Complex 50 kDa Subunit
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin in PBS with 50% Glycerol and 0.02% sodium azide.
    应用
    应用 Anti-Dynamitin (p50) Antibody, a.a. 1-83 detects level of Dynamitin (p50) & has been published & validated for use in WB.
    主要应用
    • Western Blotting
    应用说明 Western blot: 1:1,000 on mouse brain lysate.

    It is expected that the antibody will also work for immunocytochemistry and immunohistochemistry. Suggested starting 1:50.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide corresponding to aa1-83 of human Dynamitin
    表位 a.a. 1-83
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Dynamitin
    品种反应性 RabbitHumanMouseRat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_006400.3
    Entrez基因汇总 This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place.
    基因符号
    • DYNAMITIN
    • DCTN2
    • DCTN50
    • DCTN-50
    • RBP50
    UniProt编号
    • Q13561
    UniProt汇总 FUNCTION: SwissProt: Q13561 # Modulates cytoplasmic dynein binding to an organelle, and plays a role in prometaphase chromosome alignment and spindle organization during mitosis. May play a role in synapse formation during brain development.
    SIZE: 401 amino acids; 44231 Da
    SUBUNIT: Subunit of dynactin, a multiprotein complex associated with dynein. Interacts with BICD2 (By similarity). Interacts with MAPRE1.
    SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein.
    SIMILARITY: SwissProt: Q13561 ## Belongs to the dynactin subunit 2 family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,AB5869P,Anti-Dynamitin (p50) Antibody, a.a. 1-83

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