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品种反应性 主要应用 宿主 格式 抗体类型 Rhesus Macaque, M, H, R, Pm, Po, B, Eq WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABD19 Replaces MABE485 描述 Anti-Myf-5 Antibody Alternate Names - bHLHc2
- Myogenic factor 5
- Myf-5
- Class C basic helix-loop-helix protein 2
背景信息 Myogenic factor 5 (Myf-5) is a nuclear protein belonging to the Myogenic regulatory factors (MRFs) family of transcription factors characterized by their basic helix-loop-helix (bHLH) domains. The MRF family is comprised of myogenin, MyoD, MRF4, and Myf-5, and provides necessary regulatory functions in the differentiation of skeletal muscle. Myf-5, along with MyoD, is required to stimulate the differentiation of fibroblasts into myoblasts, and is likely able to bind sequence specific DNA. 产品信息 格式 Affinity Purified 控制 - Mouse e18 skeletal muscle tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-Myf-5 Antibody is a Rabbit Polyclonal Antibody for detection of Myf-5 also known as Myogenic factor 5, Myf-5 & has been validated in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human Myf-5. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Rhesus MacaqueMouseHumanRatPrimatePigBovineHorse Species Reactivity Note Demonstrated to react with Mouse, Human, and Rat. Predicted to react with Primate, Porcine, Bovine, Equine, and Rhesus Monkey based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_005584
基因符号 - BHLHC2
- MYF5
纯化方法 Affinity purified UniProt编号 - P13349
UniProt汇总 FUNCTION: Involved in muscle differentiation (myogenic factor). Induces fibroblasts to differentiate into myoblasts. Probable sequence specific DNA-binding protein.
SUBUNIT STRUCTURE: Efficient DNA binding requires dimerization with another bHLH protein.
SUBCELLULAR LOCATION: Nucleus.
SEQUENCE SIMILARITIES: Contains 1 basic helix-loop-helix (bHLH) domain.产品使用声明 质量保证 Evaluated by Western Blot in mouse e18 skeletal muscle tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Myf-5 on 10 µg of mouse e18 skeletal muscle tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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