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merck millipore,默克密理博,238811,Cdk9 Inhibitor II - CAS 140651-18-9 - Calbiochem
产品名称：Cdk9 Inhibitor II - CAS 140651-18-9 - Calbiochem
产品型号：238811
The Cdk9 Inhibitor II, also referenced under CAS 140651-18-9, controls the biological activity of Cdk9. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applicat More>>
merck millipore,默克密理博,238811,Cdk9 Inhibitor II - CAS 140651-18-9 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₉H₁₀N₆O 140651-18-9 描述 概述 A cell-permeable azo-pyrazole compound that acts as a potent, ATP-competitive, and Cdk9-selective inhibitor (IC50 = 350 nM, using Cdk9/T1). It inhibits Cdk1/B, Cdk2/E, Cdk2/A, Cdk4/D1, Cdk7/H, and p70S6K only at much higher concentrations (IC50 = 44, 20, 69, 13.5, 26, and 10 µM, respectively) and shows little or no activity against eight other commonly studied kinases even at concentrations as high as 10 µM. Shown to exhibit antiproliferative activity in human tumor cell lines. 产品目录编号 238811 品牌系列 Calbiochem®
同义词 4-(3,5-Diamino-1H-pyrazol-4-ylazo)-phenol 参考 参考 Krystof, V., et al. 2006. J. Med. Chem. 49, 6500. 产品信息 CAS号 140651-18-9 具有ATP竞争性 Y 形式 Orange solid Hill配方 C₉H₁₀N₆O 化学配方 C₉H₁₀N₆O Molar Mass 218.2 可逆 N 结构配方图像 生物信息 主靶 Cdk9 主靶IC50 350 nM, using Cdk9/T1 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or EtOH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Irritant
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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