merck millipore,默克密理博,616390,Toxin II, Anemonia sulcata - CAS 60748-45-0

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Merck Millipore 默克密理愽

merck millipore,默克密理博,616390,Toxin II, Anemonia sulcata - CAS 60748-45-0 - Calbiochem

CAS号
60748-45-0

描述
概述	Mixture of isoleucine and valine isomers. Highly toxic polypeptide. Acts specifically on Na⁺ channel in excitable membranes, affecting neuromuscular transmission and mammalian heart muscle function. Augments Na⁺-dependent increase in twitch response and the duration of action potential. Has a positive inotropic effect on the heart.
产品目录编号	616390
品牌系列	Calbiochem®
同义词	ATX II

参考
参考	Mantegazza, M., et al. 1998. J. Physiol. (London) 507 (Pt. 1), 105. Nishio, M., et al. 1991. Br. J. Pharmacol. 104, 504. Wilheim, D., et al. 1991. Br. J. Pharmacol. 104, 483. Berthold, H., et al. 1990. J. Pharmacol. Methods 24, 121. Schreibmayer, W., et al. 1987. Biochim. Biophys. Acta 901, 273. Alsen, C. 1983. Fed. Proc. 42, 101.

生物信息
生物活性	≤5 µg/kg (tested with shore crabs)
主靶	Na+ channel in excitable membranes
纯度	Approximately 40% ATX II-Ile, 40% ATX II-Val, and 20% other isotoxins by HPLC

理化信息
细胞可渗透	N
溶解度	H₂O

GHS安全信息
RTECS	CK4438200

安全信息
R相	R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed.
S相	S: 36 Wear suitable protective clothing.

储存和货运信息
货运代码	Ambient Temperature Only
毒性	Harmful
储存	+2°C to +8°C
无需冷冻	No
特殊指南	Following reconstitution, refrigerate (4°C).

merck millipore,默克密理博,616390,Toxin II, Anemonia sulcata - CAS 60748-45-0 - Calbiochem

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