merck millipore,默克密理愽
  • merck millipore,默克密理博,219511,Cdc2-Like Kinase Inhibitor IV, KH-CB19 - Calbiochem

  • merck millipore,默克密理博,219511,Cdc2-Like Kinase Inhibitor IV, KH-CB19 - Calbiochem

    产品名称：Cdc2-Like Kinase Inhibitor IV, KH-CB19 - Calbiochem
    产品型号：219511
    The Cdc2-Like Kinase Inhibitor IV, KH-CB19 controls the biological activity of Cdc2-Like KInase. This small molecule/inhibitor is primarily used for Cell Structure applications.

    merck millipore,默克密理博,219511,Cdc2-Like Kinase Inhibitor IV, KH-CB19 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,219511,Cdc2-Like Kinase Inhibitor IV, KH-CB19 - Calbiochem

    重要规格表

    经验配方
    C₁₅H₁₃Cl₂N₃O₂
    描述
    概述 A cell-permeable N-methylindolyl-enaminonitrile that acts as a potent inhibitor against CLK1, DYRK1A (IC50 = 19.7 and 55.2 nM, respectively), and likely CLK4, while exhibiting much lower potency against CLK3 (IC50 = 0.53 µM) and little activity toward a panel of 71 other protein kinases. Shown to be more effective than TG003 (Cat. No. 219479) in suppressing both basal and TNF-α-stimulated SRp55 and SRp75 phosphorylation, as well as human tissue factor spliced variants, flTF and asHTF, mRNA levels in human microvascular endothelial cells HMEC-1 (5 to 10 µM).
    产品目录编号 219511
    品牌系列 Calbiochem®
    同义词 (E)-Ethyl-3-(2-amino-1-cyanovinyl)-6,7-dichloro-1-methyl-1H-indole-2-carboxylate, Clk Inhibitor IV
    参考
    参考 Fedorov, O., et al. 2011. Chem. Biol. 18, 67.
    产品信息
    形式 White solid
    Hill配方 C₁₅H₁₃Cl₂N₃O₂
    化学配方 C₁₅H₁₃Cl₂N₃O₂
    Molar Mass 338.2
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
    毒性 Standard Handling
    储存 -20°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,219511,Cdc2-Like Kinase Inhibitor IV, KH-CB19 - Calbiochem

上一件merck millipore产品：merck millipore,默克密理博,528284,Polo-like Kinase Inhibitor III - CAS 660868-91-7 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,MAB4350,Anti-BMP-7 Antibody, clone 2A10


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