merck millipore,默克密理博,219498,Cathepsin S Substrate, Fluorogenic

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Merck Millipore 默克密理愽

merck millipore,默克密理博,219498,Cathepsin S Substrate, Fluorogenic - Calbiochem

描述
概述	An internally quenched, highly cathepsin S-selective, fluorogenic peptide substrate that is efficiently cleaved by CatS (k_cat/K_m = 1.018 µM^-1 S^-1), but not by Cathepsin B & L (k_cat/K_m = 0.004 and 0.032 µM^-1 S^-1, respectively). Studies using CatS-specific inhibitor LHVS reveal that the substrate is not cleaved by other proteolytic enzymes, including CatB, CatH, CatL, and CatX, present in endosomal extracts from human B cell line WT100, dendritic cells, and macrophages. (excitation maximum: 340 nm; emission maximum: 405 nm)
产品目录编号	219498
品牌系列	Calbiochem®
同义词	Mca-GRWPPMG~LPWEK(Dnp)-D-R-NH2

参考
参考	Lutzner, N., and Kalbacher, H. 2008. J. Biol. Chem. 283, 36185.

产品信息
形式	Yellow solid
配方	Supplied as a trifluoroacetate salt.
Hill配方	C₉₃H₁₂₃N₂₅O₂₃S
化学配方	C₉₃H₁₂₃N₂₅O₂₃S
Molar Mass	1991.2
吸湿	Hygroscopic
肽序列	Mca-Gly-Arg-Trp-Pro-Pro-Met-Gly~Leu-Pro-Trp-Glu-Lys(Dnp)-D-Arg-NH₂

生物信息
纯度	≥95% by HPLC

理化信息
溶解度	DMSO
肽序列	Mca-Gly-Arg-Trp-Pro-Pro-Met-Gly~Leu-Pro-Trp-Glu-Lys(Dnp)-D-Arg-NH₂

储存和货运信息
货运代码	Shipped with Blue Ice or with Dry Ice
毒性	Standard Handling
储存	-20°C
避光	Protect from light
吸湿	Hygroscopic
无需冷冻	No
特殊指南	Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

包装信息
惰性气体下包装	Packaged under inert gas

merck millipore,默克密理博,219498,Cathepsin S Substrate, Fluorogenic - Calbiochem

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merck millipore,默克密理博,219498,Cathepsin S Substrate, Fluorogenic - Calbiochem