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merck millipore,默克密理博,MABN643,Anti-NDUFS3 Antibody, clone 6H7.1
产品名称：Anti-NDUFS3 Antibody, clone 6H7.1
产品型号：MABN643
This Anti-NDUFS3 Antibody, clone 6H7.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of NDUFS3.
merck millipore,默克密理博,MABN643,Anti-NDUFS3 Antibody, clone 6H7.1
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, H WB M Purified Monoclonal Antibody 描述 产品目录编号 MABN643 描述 Anti-NDUFS3 Antibody, clone 6H7.1 Alternate Names - NADH-ubiquinone oxidoreductase 30 kDa subunit
- NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial
- Complex I-30kD
- CI-30kD
背景信息 NDUFS3 is the core subunit of the mitochondrial respiratory chain's NADH dehydrogenase complex, also known as Complex I, the complex critical for the production of ATP and NADH electron transfer. In mammals Complex I consists of some 45 different proteins, NDUFS3 is the critical core subunit of the complex. Expressed in all cells and localized in the mitochondria but encoded by a nuclear gene, NDUFS3 plays a critical role in electron transport, our internal cellular respiratory chain, and mitochondrial function. NDUFS3 also is important in disease phenotypes and various cancers. Mutations in NDUFS3 give rise to Leigh syndrome a mitochondrial dysfunctional disease. In cancers, down regulation of NDUFS3 is linked with lowered host survival and increased cancer pathology. 产品信息 格式 Purified 演示 Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-NDUFS3 Antibody, clone 6H7.1 is validated for use in Western Blotting and Immunohistochemistry (Paraffin) for the detection of NDUFS3. 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected NDUFS3 in human cerebral cortex, rat hippocampus, and rat cerebellum tissue. 生物信息 免疫原品种 GST-tagged recombinant protein corresponding to human NDUFS3. 克隆 6H7.1 浓缩 Please refer to lot specific datasheet. 宿主 Mouse 同种型 IgG1κ 品种反应性 RatHuman Species Reactivity Note Human, Rat. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_004542
基因符号 - NDUFS3
纯化方法 Protein G purified UniProt编号 - O75489
产品使用声明 质量保证 Evaluated by Western Blotting in THP-1 cell lysate.
Western Blotting Analysis: 1.0 µg/mL of this antibody detected NDUFS3 in 200 µg of THP-1 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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