merck millipore,默克密理愽
  • merck millipore,默克密理博,217694,Cdc25 Inhibitor IV, NSC 95397 - CAS 93718-83-3 - Calbiochem

  • merck millipore,默克密理博,217694,Cdc25 Inhibitor IV, NSC 95397 - CAS 93718-83-3 - Calbiochem

    产品名称：Cdc25 Inhibitor IV, NSC 95397 - CAS 93718-83-3 - Calbiochem
    产品型号：217694
    The Cdc25 Inhibitor IV, NSC 95397, also referenced under CAS 93718-83-3, controls the biological activity of Cdc25. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylat More>>

    merck millipore,默克密理博,217694,Cdc25 Inhibitor IV, NSC 95397 - CAS 93718-83-3 - Calbiochem

  • 产品介绍
  • merck millipore,默克密理博,217694,Cdc25 Inhibitor IV, NSC 95397 - CAS 93718-83-3 - Calbiochem

    重要规格表

    经验配方 CAS号
    C₁₄H₁₄O₄S₂93718-83-3
    描述
    概述 A cell-permeable, para-naphthoquinone that has been reported to inhibit protein tyrosine phosphatase activity, including Cdc25 dual specificity phosphatase (Ki = 32 nM, 96 nM, and 40 nM for Cdc25A, -B, and -C, respectively) and blocks G2M transition in murine carcinoma cells. In addition, it is shown to inhibit S100A4 binding to myosin-IIA via covalent modification of cysteine residues, Cys81 and Cys86, in the target binding cleft (IC50 = 1.8 µM). It demonstrates inhibitory activity against S100A4-mediated depolymerization of myosin-IIA filaments.
    产品目录编号 217694
    品牌系列 Calbiochem®
    同义词 (2,3-bis-[2-hydroxyethylsulfanyl]-[1,4]naphthoquinone), PTP Inhibitor XXIX
    参考
    参考 Dulyaninova, N.G., et al. 2011. Biochemistry 50, 7218.
    Lazo, J.S., et al. 2002. Mol. Pharmacol. 61, 720.
    产品信息
    CAS号 93718-83-3
    形式 Orange solid
    Hill配方 C₁₄H₁₄O₄S₂
    化学配方 C₁₄H₁₄O₄S₂
    Molar Mass 310.39
    结构配方图像
    生物信息
    纯度 ≥95% by HPLC
    理化信息
    溶解度 DMSO
    储存和货运信息
    货运代码 Ambient Temperature Only
    毒性 Standard Handling
    储存 +2°C to +8°C
    避光 Protect from light
    无需冷冻 No
    特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
    包装信息
    惰性气体下包装 Packaged under inert gas

    merck millipore,默克密理博,217694,Cdc25 Inhibitor IV, NSC 95397 - CAS 93718-83-3 - Calbiochem

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