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merck millipore,默克密理博,124008,Akt Inhibitor II - Calbiochem
产品名称：Akt Inhibitor II - Calbiochem
产品型号：124008
The Akt Inhibitor II controls the biological activity of Akt. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
merck millipore,默克密理博,124008,Akt Inhibitor II - Calbiochem
- 产品介绍
重要规格表
经验配方 C₂₉H₅₉O₁₀P 描述 概述 A cell permeable, reversible, and substrate competitive phosphatidylinositol analog that inhibits the activation of Akt and select downstream substrates without decreasing phosphorylation of PDK-1 or other kinases downstream of Ras, such as MAPK. Also acts as a potent inducer of apoptosis and selectively kills a variety of cancer cell lines that contain high levels of active Akt. When used at a concentration of 10 µM, it is reported to activate p38α/SAPK2α MAP kinase. At 10 µM it will also inhibit ~50% of PKA activity. 产品目录编号 124008 品牌系列 Calbiochem®
同义词 SH-5 参考 参考 Gills, J.J., et al. 2007. J. Biol. Chem. in press.
Kozikowski, A.P., et al. 2003. J. Am. Chem. Soc.125, 1144.产品信息 具有ATP竞争性 N 形式 White solid Hill配方 C₂₉H₅₉O₁₀P 化学配方 C₂₉H₅₉O₁₀P Molar Mass 598.7 可逆 Y 结构配方图像 生物信息 主靶 Akt 纯度 ≥98% by NMR 理化信息 细胞可渗透 Y 溶解度 DMSO 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
无需冷冻 No
特殊指南 Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
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