merck millipore,默克密理博,CBL1337F,Anti-PECAM-1 Antibody, clone 390, FITC conjugated

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M	IHC, FC	R	FITC	Monoclonal Antibody

描述
产品目录编号	CBL1337F
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-PECAM-1 Antibody, clone 390, FITC conjugated
Alternate Names	CD31
背景信息	PECAM-1 is a type I integral membrane glycoprotein, and a member of the immunoglobulin superfamily of cell surface receptors. PECAM-1 is constitutively expressed on the surface of endothelial cells where it is concentrated at cell junctions. PECAM-1 is also expressed at low levels on all leukocytes and platelets. Homotypic interaction of CD31 is important in cell-cell interaction, cell-matrix interaction and signal transduction.

产品信息
格式	FITC
演示	Purified immunoglobulin conjugated to fluorescein. Liquid in in phosphate buffered saline containing 0.1% sodium azide.

应用
应用	This Anti-PECAM-1 Antibody, clone 390, FITC conjugated is validated for use in FC, IH for the detection of PECAM-1.
主要应用	Immunohistochemistry Flow Cytometry
应用说明	Flow Cytometry: = 1 μg per 10e6 cells in 100 μL volume Immunohistochemistry: acteone fixed frozen tissue sections. Optimal working dilutions must be determined by the end user.

生物信息
免疫原品种	Mouse leukocyte cell line 32D
克隆	390
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rat
特异性	CBL1337 recognizes mouse PECAM-1, a 130-140 kDa type 1 integral membrane glycoprotein. This antibody has been shown to inhibit the aggregation of L cells transfected with a variant form of PECAM-1 (DeLisser, 1993).
同种型	IgG2aκ
品种反应性	Mouse
抗体类型	Monoclonal Antibody
Entrez基因编号	NM_000442.3
基因符号	CD31/EndoCAM PECAM1 EndoCAM GPIIA PECAM-1 CD31
UniProt编号	P16284
UniProt汇总	FUNCTION: SwissProt: P16284 # This protein is a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. SIZE: 738 amino acids; 82536 Da SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein. TISSUE SPECIFICITY: Long isoform predominates all tissues examined, isoform Delta12 was detected only in trachea and isoform Delta14-15 only in lung, isoform Delta14 was detected in all tissues examined with the strongest expression in heart. PTM: Phosphorylated on Ser and Tyr residues after cellular activation. SIMILARITY: SwissProt: P16284 ## Contains 6 Ig-like C2-type (immunoglobulin-like) domains.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain at 2°-8°C for up to 12 months from date of receipt. DO NOT FREEZE.

包装信息
数量	500 µg

merck millipore,默克密理博,CBL1337F,Anti-PECAM-1 Antibody, clone 390, FITC conjugated

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