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merck millipore,默克密理博,208902,Calpastatin Peptide - Calbiochem
产品名称:Calpastatin Peptide - Calbiochem
产品型号:208902
A 27-amino acid, cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC₅₀ = 20 nM for purified rabbit calpain II).
merck millipore,默克密理博,208902,Calpastatin Peptide - Calbiochem
- 产品介绍
重要规格表
经验配方 C₁₄₂H₂₃₀N₃₆O₄₄S 描述 概述 A 27-amino acid, cell-permeable peptide encoded by exon 1B of human calpastatin that acts as a potent inhibitor of calpain I and calpain II (IC50 = 20 nM for purified rabbit calpain II). Does not inhibit either papain or trypsin. Blocks the down-regulation of protein kinase Cε (PKCε) in rat pituitary GH4C1 cells stimulated by thyrotropin-releasing hormone (TRH). 产品目录编号 208902 品牌系列 Calbiochem®
同义词 CS Peptide 参考 参考 Eto, A., et al. 1995. J. Biol. Chem. 270, 25115.
Kawasaki, J., et al. 1989. J. Biochem. 106, 274.
Maki, M., et al. 1989. J. Biol. Chem. 264, 18866.产品信息 具有ATP竞争性 N 形式 White lyophilized solid 配方 Supplied as a trifluoroacetate salt. Hill配方 C₁₄₂H₂₃₀N₃₆O₄₄S 化学配方 C₁₄₂H₂₃₀N₃₆O₄₄S Molar Mass 3177.7 吸湿 Hygroscopic
肽序列 Ac-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-NH₂ 可逆 N 生物信息 主靶 calpain 2 主靶IC50 20 nM against calpain II 纯度 ≥95% by HPLC 理化信息 细胞可渗透 Y 溶解度 H₂O or 1% Acetic Acid 肽序列 Ac-Asp-Pro-Met-Ser-Ser-Thr-Tyr-Ile-Glu-Glu-Leu-Gly-Lys-Arg-Glu-Val-Thr-Ile-Pro-Pro-Lys-Tyr-Arg-Glu-Leu-Leu-Ala-NH₂ 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 -20°C
吸湿 Hygroscopic
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
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